제1형 신경섬유종증에서 발생한 양측성 이시성 유방암

다국어 초록 (Multilingual Abstract)

Neurofibromatosis type 1 (NF1) is an autosomal dominant disease, characterized by cafe-au-lait spot, axillary and inguinal freckle, peripheral neurofibroma and pigmented iris hamartoma. The various cancer incidences are increased in the NF1. But NF1 with breast cancer is rare. In this report we present a case of a 46?year?old NF1 female with a bilateral metachronous breast cancer. The patient has no BRCA2 mutation, but there are two unclassified variants in the exon 11 of BRCA1. The possibility of LOH of BRCA1 gene in the cancer tissue cannot be excluded.

목차 (Table of Contents)

• 서론
• 증례
• 고찰
• REFERENCES

참고문헌 (Reference)

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