The antioxidant capacity and protective effect of peptides from protein hydrolysate of Cordyceps militaris cultivated with tussah pupa (ECPs) on H<sub>2</sub>O<sub>2</sub>-injured HepG2 cells were studied. Results indicated ECP...
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https://www.riss.kr/link?id=A109221142
Bingxin Li ; Jinying Zhang ; Yefei Liu ; Ze Wang ; Fangxu Xu
2024
English
SCIE,SCOPUS,KCI등재
학술저널
1082-1091(10쪽)
0
상세조회0
다운로드다국어 초록 (Multilingual Abstract)
The antioxidant capacity and protective effect of peptides from protein hydrolysate of Cordyceps militaris cultivated with tussah pupa (ECPs) on H<sub>2</sub>O<sub>2</sub>-injured HepG2 cells were studied. Results indicated ECP...
The antioxidant capacity and protective effect of peptides from protein hydrolysate of Cordyceps militaris cultivated with tussah pupa (ECPs) on H<sub>2</sub>O<sub>2</sub>-injured HepG2 cells were studied. Results indicated ECP1 (<3 kDa) presented the strongest antioxidant activity compared with other molecular weight peptides. Pretreated with ECPs observably enhanced survival rates and reduced apoptosis rates of HepG2 cells. ECPs treatment decreased the ROS level, MDA content and increased CAT and GSH-Px activities of HepG2 cells. Besides, the morphologies of natural peptides from C. militaris cultivated with tussah pupa (NCP1) and ECP1 were observed by scanning electron microscopy (SEM). Characterization results suggested the structure of NCP1 was changed by enzymatic hydrolysis treatment. Most of hydrophobic and acidic amino acids contents (ACC) in ECP1 were also observably improved by enzymatic hydrolysis. In conclusion, low molecular weight peptides had potential value in the development of cosmetics and health food.
Campylobacteriosis and Control Strategies against Campylobacters in Poultry Farms