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      정신분열병 입원 환자에서의 대사 증후군 유병률 연구 = The Prevalence of Metabolic Syndrome in Inpatients with Schizophrenia

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      https://www.riss.kr/link?id=A101641010

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      다국어 초록 (Multilingual Abstract)

      Objectives : The objective of this study is to assess the prevalence and risk factors of metabolic syndrome (MS) among inpatients with schizophrenia, and to compare with general population. Methods : Nine hundreds seventy inpatients were included to assess the prevalence of MS from two mental hospitals in Yong-in city. Assessment of MS was performed based on modified American Heart Association criteria with abdominal obesity threshold of 90cm for men, 85cm for women. Comparative analysis was performed using age- and gender matched sample from Korea Health and Nutritional Examination Survey III. For evaluating risk factors, analysis included 766 inpatients taking consistent medications at least for 30 days. Results : The prevalence of MS of inpatients with schizophrenia was 26.2%, in females it was 33.2%, compared to 20.2% in males(p < 0.001). Compared to general population, the prevalence of MS was significantly lower in male and higher in female patients. In terms of criteria prevalence, who met abdominal circumference criterion were more prevalent in patient group(p < 0.001). After multivariate analysis, female gender and old age remained as risk factors of MS. Conclusions : The prevalence of MS of inpatients with schizophrenia was 26.2% and significantly low compared to general population. Female gender and old age were risk factors of MS.
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      Objectives : The objective of this study is to assess the prevalence and risk factors of metabolic syndrome (MS) among inpatients with schizophrenia, and to compare with general population. Methods : Nine hundreds seventy inpatients were included to a...

      Objectives : The objective of this study is to assess the prevalence and risk factors of metabolic syndrome (MS) among inpatients with schizophrenia, and to compare with general population. Methods : Nine hundreds seventy inpatients were included to assess the prevalence of MS from two mental hospitals in Yong-in city. Assessment of MS was performed based on modified American Heart Association criteria with abdominal obesity threshold of 90cm for men, 85cm for women. Comparative analysis was performed using age- and gender matched sample from Korea Health and Nutritional Examination Survey III. For evaluating risk factors, analysis included 766 inpatients taking consistent medications at least for 30 days. Results : The prevalence of MS of inpatients with schizophrenia was 26.2%, in females it was 33.2%, compared to 20.2% in males(p < 0.001). Compared to general population, the prevalence of MS was significantly lower in male and higher in female patients. In terms of criteria prevalence, who met abdominal circumference criterion were more prevalent in patient group(p < 0.001). After multivariate analysis, female gender and old age remained as risk factors of MS. Conclusions : The prevalence of MS of inpatients with schizophrenia was 26.2% and significantly low compared to general population. Female gender and old age were risk factors of MS.

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      참고문헌 (Reference)

      1 남윤영, "만성 정신분열병 환자들의 대사증후군과 관련된 임상 특징들" 대한정신약물학회 17 (17): 335-341, 2006

      2 Stahl SM, "Which comes first: atypical antipsychotic treatment or cardiometabolic risk" 119 : 171-179, 2009

      3 Reynolds MF, "Valproate and neuroendocrine changes in relation to women treated for epilepsy and bipolar disorder: a review" 14 : 2799-2812, 2007

      4 Teixeira PJ, "The prevalence of metabolic syndrome among psychiatric inpatients in Brazil" 29 : 330-336, 2007

      5 Alberti KG, "The metabolic syndrome-- a new worldwide definition" 366 : 1059-1062, 2005

      6 Kylin E, "Studien ueber das hypertonie-hyperglykmie-hyperurikmiesyndrome" 44 : 105-127, 1923

      7 Reaven GM, "Role of insulin in regulation of lipoprotein metabolism in diabetes" 4 : 639-652, 1988

      8 McEvoy JP, "Prevalence of the metabolic syndrome in patients with schizophrenia: baseline results from the Clinical Antipsychotic Trials of Intervention Effectiveness( CATIE) schizophrenia trial and comparison with national estimates from NHANES III" 80 : 19-32, 2005

      9 Ford ES, "Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey" 287 : 356-359, 2002

      10 Ford ES, "Prevalence of the metabolic syndrome among U.S. adolescents using the definition from the International Diabetes Federation" 31 : 587-589, 2008

      1 남윤영, "만성 정신분열병 환자들의 대사증후군과 관련된 임상 특징들" 대한정신약물학회 17 (17): 335-341, 2006

      2 Stahl SM, "Which comes first: atypical antipsychotic treatment or cardiometabolic risk" 119 : 171-179, 2009

      3 Reynolds MF, "Valproate and neuroendocrine changes in relation to women treated for epilepsy and bipolar disorder: a review" 14 : 2799-2812, 2007

      4 Teixeira PJ, "The prevalence of metabolic syndrome among psychiatric inpatients in Brazil" 29 : 330-336, 2007

      5 Alberti KG, "The metabolic syndrome-- a new worldwide definition" 366 : 1059-1062, 2005

      6 Kylin E, "Studien ueber das hypertonie-hyperglykmie-hyperurikmiesyndrome" 44 : 105-127, 1923

      7 Reaven GM, "Role of insulin in regulation of lipoprotein metabolism in diabetes" 4 : 639-652, 1988

      8 McEvoy JP, "Prevalence of the metabolic syndrome in patients with schizophrenia: baseline results from the Clinical Antipsychotic Trials of Intervention Effectiveness( CATIE) schizophrenia trial and comparison with national estimates from NHANES III" 80 : 19-32, 2005

      9 Ford ES, "Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey" 287 : 356-359, 2002

      10 Ford ES, "Prevalence of the metabolic syndrome among U.S. adolescents using the definition from the International Diabetes Federation" 31 : 587-589, 2008

      11 Boke O, "Prevalence of metabolic syndrome among inpatients with schizophrenia" 38 : 103-112, 2008

      12 Park HS, "Prevalence and trends of metabolic syndrome in Korea: Korean National Health and Nutrition Survey 1998-2001" 9 : 50-58, 2007

      13 Choi KM, "Prevalence and cardiovascular disease risk of the metabolic syndrome using National Cholesterol Education Program and International Diabetes Federation definitions in the Korean population" 56 : 552-558, 2007

      14 Yoon BH, "Prevalence and Characteristics of Metabolic Syndrome in Schizophrenic Inpatient" 2008

      15 Osby U, "Mortality and causes of death in schizophrenia in Stockholm county, Sweden" 45 : 21-28, 2000

      16 Batsis JA, "Metabolic syndrome: from global epidemiology to individualized medicine" 82 : 509-524, 2007

      17 Lee NY, "Metabolic syndrome in patients with Schizophrenia and Bipolar disorder: comparision with general population" 2008

      18 De Hert M, "Me tabolic syndrome in people with schizophrenia: a review" 8 : 15-22, 2009

      19 Suvisaari JM, "Lonnqvist J, et al. Metabolic syndrome among persons with schizophrenia and other psychotic disorders in a general population survey" 68 : 1045-1055, 2007

      20 Seo I, "In-Depth Analysis on the 3rd Korea Health and Nutrition Examination Survey" 167-193, 2007

      21 "Executive Summary of The Third Report of The National Cholesterol Education Program(NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults(Adult Treatment Panel III)" 285 : 2486-2497, 2001

      22 Pan WH, "Epidemiology of metabolic syndrome in Asia" 17 (17): 37-42, 2008

      23 Association AP, "Diagnostic and Statistical Manual of Mental Disorders(DSM-IV-TR). 4th evidence-based text revision ed" American Psychiatric Association 2000

      24 Grundy SM, "Diagnosis and management of the metabolic syndrome: an American Heart Association/ National Heart, Lung, and Blood Institute Scientific Statement" 112 : 2735-2752, 2005

      25 Alberti KG, "Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation" 15 : 539-553, 1998

      26 Cohn T, "Characterizing coronary heart disease risk in chronic schizophrenia: high prevalence of the metabolic syndrome" 49 : 753-760, 2004

      27 Lee SY, "Appropriate waist circumference cutoff points for central obesity in Korean adults" ELSEVIER IRELAND LTD 75 (75): 72-80, 2007

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      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.19 0.19 0.19
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.14 0.15 0.475 0
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