HCC : PE-077 ; Primary adenosquamous carcinoma of the liver: A case report = HCC : PE-077 ; Primary adenosquamous carcinoma of the liver: A case report

다국어 초록 (Multilingual Abstract)

Background: Adenosquamouscarcinoma is a rare tumor of the liver, which carries a poor prognosis. It has been reported mostly in form of case studies. From five hepatobiliary ASC for the past 10 years in our institute, one primary hepatic ASC was observed. We describe a case of primary hepatic ASC preoperatively diagnosed as CCC, and attempting to explore it clinicopathologically. Case: We experienced a case of primary adenosquamous carcinoma of the liver preoperatively considered as cholangiocelluar carcinoma (CCC) of the liver. MRI from our hospital showed 5cm sized lobulated mass with dilatation of peritumoral intrahepatic duct (IHD) in Left segment of the liver which was consistent with hepatic CCC and no evidence of any abnormal lymphadenopathy in significant size. Microscopically, the tumor was composed of adenocarcinoma, squamous cell carcinoma as well as transitional area including the transformation of adenocarcinoma to squamous cell carcinoma. Conclusions: In our case, microscopically the tumor was composed of adenocarcinoma, squamous cell carcinoma as well as transitional area including the transformation of adenocarcinoma to squamous cell carcinoma. This is in accordance with the microscopic studies of four other hepatobiliary carcinoma of our institute. The adenocarcinoma component arising from the main biliary duct seemed to differentiate into the squamous cell carcinoma component.