Rhinovirus Associated Severe Respiratory Failure in Immunocompetent Adult Patient

다국어 초록 (Multilingual Abstract)

Rhinovirus infection is typically associated with the common cold and has rarely been reported as a cause of severe pneumonia in immunocompetent adults. A 55-year-old previous healthy woman, who consumed half a bottle of alcohol daily, presented with respiratory failure after one week of upper respiratory infection symptoms. Radiography revealed bilateral, diffuse ground glass opacity with patchy consolidation in the whole lung field; bronchoalveolar lavage fluid analysis indicated that rhinovirus was the causative organism. After five days of conservative support, the symptoms and radiographic findings began to improve. We report this rare case of rhinovirus pneumonia in an otherwise healthy host along with a review of references.

참고문헌 (Reference)

1 Hobson D, "Virological studies in natural common colds in Sheffield in 1960" 2 : 1414-1418, 1960

2 Ruuskanen O, "Viral pneumonia" 377 : 1264-1275, 2011

3 Choi SH, "Viral infection in patients with severe pneumonia requiring intensive care unit admission" 186 : 325-332, 2012

4 Johnstone J, "Viral infection in adults hospitalized with community-acquired pneumonia:prevalence, pathogens, and presentation" 134 : 1141-1148, 2008

5 Hicks LA, "Two outbreaks of severe respiratory disease in nursing homes associated with rhinovirus" 54 : 284-289, 2006

6 Joshi PC, "The alcoholic lung: epidemiology, pathophysiology, and potential therapies" 292 : L813-L823, 2007

7 Calvo C, "Role of rhinovirus in hospitalized infants with respiratory tract infections in Spain" 26 : 904-908, 2007

8 Longtin J, "Rhinovirus outbreaks in long-term care facilities, Ontario, Canada" 16 : 1463-1465, 2010

9 Louie JK, "Rhinovirus associated with severe lower respiratory tract infections in children" 28 : 337-339, 2009

10 Hayden FG, "Rhinovirus and the lower respiratory tract" 14 : 17-31, 2004

11 Nicholson KG, "Respiratory viruses and exacerbations of asthma in adults" 307 : 982-986, 1993

12 Forsyth BR, "Patterns of illness in rhinovirus infections of military personnel" 269 : 602-606, 1963

13 Pang M, "Inhibition of TLR8- and TLR4-induced Type I IFN induction by alcohol is different from its effects on inflammatory cytokine production in monocytes" 12 : 55-, 2011

14 Jennings LC, "Incidence and characteristics of viral community-acquired pneumonia in adults" 63 : 42-48, 2008

15 Polikandriotis JA, "Chronic ethanol ingestion increases superoxide production and NADPH oxidase expression in the lung" 34 : 314-319, 2006