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あぁかがさざただなはばぱまやゃらわゎんいぃきぎしじちぢにひびぴみりうぅくぐすずつづっぬふぶぷむゆゅるえぇけげせぜてでねへべぺめれおぉこごそぞとどのほぼぽもよょろを

アァカサザタダナハバパマヤャラワヮンイィキギシジチヂニヒビピミリウゥクグスズツヅッヌフブプムユュルエェケゲセゼテデヘベペメレオォコゴソゾトドノホボポモヨョロヲ ―

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á à Á À é è É È ç Ç ê

Ä Ö Ü ä ö ü ß

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RISS 인기검색어

HRccine(HFRS-virus vaccine)의 Rat에서의 아급성독성 = Subacute Toxicity of HRccine (HFRS-virus vaccine) in Rats

한글로보기

https://www.riss.kr/link?id=A106721066

저자

조효진 ; 백영옥 ; 임동문 ; 최재묵 ; 김달현 ; 박관하 ; 조정식 ; 이영순
발행기관
한국독성학회
학술지명
Toxicological Research(Toxicological Research)
권호사항

Vol.11 No.1 [1995]
발행연도
1995
작성언어
Korean
주제어

HRccine ; Rats ; Subacute Toxicity
등재정보
SCOPUS,KCI등재,SCIE
자료형태
학술저널
발행기관 URL
http://www.toxmut.or.kr
수록면

137-145(9쪽)
제공처
ScienceON
소장기관
- 덕성여자대학교 중앙도서관

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다국어 초록 (Multilingual Abstract)

HRccine was administered subcutaneously to rats for 4 weeks at dose levels of 300, 60 and 12 times the expected clinical dose to evaluate the subacute toxicity. There were no treatment-related effects in clinical signs, body weight changes, food consumption, water consumption, urinalysis and blood biochemistry in any dose groups. In hematological examinations, increase of leucocyte counts and decrease of hemoglobin concentration were observed in the high dose-treated group. However, no treatment-attributable pathological changes were observed in microscopic examinations. The no-effect dose in subacute toxicity study of rats was considered to be 300 times the expected clinical dose.

번역하기

HRccine was administered subcutaneously to rats for 4 weeks at dose levels of 300, 60 and 12 times the expected clinical dose to evaluate the subacute toxicity. There were no treatment-related effects in clinical signs, body weight changes, food consu...

HRccine was administered subcutaneously to rats for 4 weeks at dose levels of 300, 60 and 12 times the expected clinical dose to evaluate the subacute toxicity. There were no treatment-related effects in clinical signs, body weight changes, food consumption, water consumption, urinalysis and blood biochemistry in any dose groups. In hematological examinations, increase of leucocyte counts and decrease of hemoglobin concentration were observed in the high dose-treated group. However, no treatment-attributable pathological changes were observed in microscopic examinations. The no-effect dose in subacute toxicity study of rats was considered to be 300 times the expected clinical dose.