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      기면증의 뇌형태 변화 = Morphological Changes in Narcolepsy

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      다국어 초록 (Multilingual Abstract)

      Narcolepsy is a chronic neurological disorder with the abnormal regulation of the sleep-wake cycle, resulting in excessive daytime sleepiness, disturbed nocturnal sleep, and manifestations related to REM sleep such as cataplexy, sleep paralysis, and hypnagogic hallucination. Over the past decade, numerous neuroimaging studies, have been performed to characterize the pathophysiology and various clinical features of narcolepsy. Here we review structural findings based on brain magnetic resonance imaging in narcolepsy with cataplexy, which include voxel-based morphometry, cortical thickness analyses, and hippocampal volumetry. The current state of research suggests that structural neuroimaging is a useful tool to investigate and understand the anatomical correlates and brain abnormalities of narcolepsy.
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      Narcolepsy is a chronic neurological disorder with the abnormal regulation of the sleep-wake cycle, resulting in excessive daytime sleepiness, disturbed nocturnal sleep, and manifestations related to REM sleep such as cataplexy, sleep paralysis, and h...

      Narcolepsy is a chronic neurological disorder with the abnormal regulation of the sleep-wake cycle, resulting in excessive daytime sleepiness, disturbed nocturnal sleep, and manifestations related to REM sleep such as cataplexy, sleep paralysis, and hypnagogic hallucination. Over the past decade, numerous neuroimaging studies, have been performed to characterize the pathophysiology and various clinical features of narcolepsy. Here we review structural findings based on brain magnetic resonance imaging in narcolepsy with cataplexy, which include voxel-based morphometry, cortical thickness analyses, and hippocampal volumetry. The current state of research suggests that structural neuroimaging is a useful tool to investigate and understand the anatomical correlates and brain abnormalities of narcolepsy.

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      참고문헌 (Reference)

      1 Brenneis C, "Voxel-based morphometry in narcolepsy" 664 : 531-536, 2005

      2 Overeem S, "Voxel-based morphometry in hypocretin-deficient narcolepsy" 26 : 44-46, 2003

      3 Taheri S, "The role of hypocretins (orexins) in sleep regulation and narcolepsy" 25 : 283-313, 2002

      4 Thannickal TC, "Reduced number of hypocretin neurons in human narcolepsy" 27 : 469-474, 2000

      5 Buskova J, "Reduced hypothalamic gray matter in narcolepsy with cataplexy" 27 : 769-772, 2006

      6 Kaufmann C, "Reduced cortical gray matter in narcolepsy: preliminary findings with voxel-based morphometry" 58 : 1852-1855, 2002

      7 Plazzi G, "Pontine lesions in idiopathic narcolepsy" 46 : 1250-1254, 1996

      8 Sakurai T, "Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior" 92 : 573-585, 1998

      9 Desseilles M, "Neuroimaging insights into the pathophysiology of sleep disorders" 31 : 777-794, 2008

      10 Fischl B, "Measuring the thickness of the human cerebral cortex from magnetic resonance images" 97 : 11050-11055, 2000

      1 Brenneis C, "Voxel-based morphometry in narcolepsy" 664 : 531-536, 2005

      2 Overeem S, "Voxel-based morphometry in hypocretin-deficient narcolepsy" 26 : 44-46, 2003

      3 Taheri S, "The role of hypocretins (orexins) in sleep regulation and narcolepsy" 25 : 283-313, 2002

      4 Thannickal TC, "Reduced number of hypocretin neurons in human narcolepsy" 27 : 469-474, 2000

      5 Buskova J, "Reduced hypothalamic gray matter in narcolepsy with cataplexy" 27 : 769-772, 2006

      6 Kaufmann C, "Reduced cortical gray matter in narcolepsy: preliminary findings with voxel-based morphometry" 58 : 1852-1855, 2002

      7 Plazzi G, "Pontine lesions in idiopathic narcolepsy" 46 : 1250-1254, 1996

      8 Sakurai T, "Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior" 92 : 573-585, 1998

      9 Desseilles M, "Neuroimaging insights into the pathophysiology of sleep disorders" 31 : 777-794, 2008

      10 Fischl B, "Measuring the thickness of the human cerebral cortex from magnetic resonance images" 97 : 11050-11055, 2000

      11 Kabani N, "Measurement of cortical thickness using an automated 3-D algorithm: a validation study" 13 : 375-380, 2001

      12 Bassetti C, "MRI findings in narcolepsy" 20 : 630-631, 1997

      13 Draganski B, "Hypothalamic gray matter changes in narcoleptic patients" 8 : 1186-1188, 2002

      14 Nishino S, "Hypocretin (orexin) deficiency in human narcolepsy" 355 : 39-40, 2000

      15 Joo EY, "Hippocampal volume and memory in narcoleptics with cataplexy" 13 : 396-401, 2012

      16 주은연, "Gray Matter Concentration Abnormality in Brains of Narcolepsy Patients" 대한영상의학회 10 (10): 552-558, 2009

      17 Joo EY, "Glucose hypometabolism of hypothalamus and thalamus in narcolepsy" 56 : 437-440, 2004

      18 Im K, "Gender difference analysis of cortical thickness in healthy young adults with surface-based methods" 31 : 31-38, 2006

      19 Schulz H, "Cognitive deficits in patients with daytime sleepiness" 97 : 108-112, 1997

      20 Joo EY, "Cerebral perfusion abnormality in narcolepsy with cataplexy" 28 : 410-416, 2005

      21 Rieger M, "Attention deficits in patients with narcolepsy" 26 : 36-43, 2003

      22 Joo EY, "Analysis of cortical thickness in narcolepsy patients with cataplexy" 34 : 1357-1364, 2011

      23 Frey JL, "Absence of pontine lesions in narcolepsy" 48 : 1097-1099, 1997

      24 Good CD, "A voxel-based morphometric study of ageing in 465 normal adult human brains" 14 (14): 21-36, 2001

      25 Hutton C, "A comparison between voxel-based cortical thickness and voxel-based morphometry in normal aging" 48 : 371-380, 2009

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      공동연구자 (7)

      유사연구자 (20) 활용도상위20명

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2026 평가예정 재인증평가 신청대상 (재인증)
      2020-01-01 평가 등재학술지 유지 (재인증) KCI등재
      2017-01-01 평가 등재학술지 선정 (계속평가) KCI등재
      2015-09-23 학술지명변경 한글명 : 수면 -> Journal of sleep medicine
      외국어명 : Journal of Korean Sleep Research Society -> Journal of sleep medicine
      KCI등재후보
      2015-01-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.11 0.11 0.13
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.11 0.1 0.4 0
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