초음파 기반 마찰전기 발전소자를 이용한 체내 삽입형 신경자극기

다국어 초록 (Multilingual Abstract)

Given that implantable medical devices are designed for long-term operation while being implanted inside the human body, it is of paramount importance to ensure a sustainable power source. The utilization of wireless power transfer technology for the continuous supply of energy has been constrained by the necessity for titanium packaging, which is essential for achieving both long-term biocompatibility and the hermetic sealing of the device. In this study, we implemented a battery-free miniaturized neurostimulator using an ultrasound-driven implantable triboelectric nanogenerator, which can harvest energy through titanium packaging. This medical device efficiently delivers sufficient power to generate stimulation pulses and has demonstrated its efficacy in alleviating symptoms associated with urinary tract complications in in-vivo demonstration using a rat model. These accomplishments mark significant advancements in the development of devices that are permanently implantable for treating intractable diseases.