Vitamin C can improve the efficiency of existing reprogramming protocols for human somatic cells, including fibroblasts and nonfibroblasts. Mesotherapy represents a variety of minimally invasive techniques in which medications are directly injected in...
Vitamin C can improve the efficiency of existing reprogramming protocols for human somatic cells, including fibroblasts and nonfibroblasts. Mesotherapy represents a variety of minimally invasive techniques in which medications are directly injected into the skin and underlying tissue. This study evaluated the effects of and satisfaction with skin care using vitamin C and mesotherapy. Twenty three middle-aged women underwent ten sessions of skin care (control group, n=11; mesotherapy group, n=12). The mesotherapy group was treated with mesotherapy along with the application of vitamin C, while the control group received application of vitamin C only. All subjects were treated once a week for a period of 10 weeks. Via survey, the self-reported skin status regarding pigmentation in the mesotheraopy group was found to have improved more as compared to the control group. In the mesotherapy group, brightness, yellow tones and chroma differed significantly according to measurement points. Chrominances between 0 week and 5 weeks, and 5 weeks and 10 weeks differed significantly in the control group and mesotherapy group. Satisfaction with skin care in the mesotherapy group was significantly higher than in the control group. These results indicated that mesotherapy is an effective alternative treatment modality for aging skin in middle-aged women.