신식물육종기술의 현황과 사회적 수용을 위한 노력 = Current status of new plant breeding technology and its efforts toward social acceptance

다국어 초록 (Multilingual Abstract)

Although new plant breeding technologies facilitate efficient plant breeding without introducing a transgene, they are creating indistinct boundaries in the regulation of genetically modified organisms (GMOs). The rapid advancement in plant breeding by genome-editing requires the establishment of a new global policy for the new biotechnology, while filling the gap between process-based and product-based GMO in terms of regulations. In this study recent developments in producing major crops using new plant breeding technologies were reviewed, and a regulatory model that takes into account the various methodologies to achieve genetic modifications as well as the resulting types of mutation were proposed. Moreover, the communication process were discussed in order to understand consumers’ current situation and problems of new plant breeding technology, establish social acceptance well, and understand consumers’ disputes such as GMO crops.

참고문헌 (Reference)

1 정유진, "벼에서 CRISPR/Cas9 활용 고빈도 유전자 편집 방법" 한국식물생명공학회 44 (44): 89-96, 2017

2 Durai S, "Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells" 18 : 5978-5990, 2005

3 Cellini F, "Unintended effects and their detection in genetically modified crops" 42 : 1089-1125, 2004

4 Rose NR, "Understanding the relationship between DNA methylation and histone lysine methylation" 1839 : 1362-1372, 2014

5 Araki M, "Towards social acceptance of plant breeding by genome editing" 1257-, 2015

6 ACRE, "The criteria used by ACRE to gauge harm when giving advice on the risks of releasing genetically modified organisms to the environment"

7 Fan J, "The GM corn carcinogenic study and the proper reasoning on controversial research" 25 : 552-559, 2013

8 Quétier F, "The CRISPR-Cas9 technology: Closer to the ultimate toolkit for targeted genome editing" 242 : 65-76, 2016

9 Joung JK, "TALENs: a widely applicable technology for targeted genome editing" 14 : 49-55, 2013

10 Podevin N, "Site-directed nucleases: a paradigm shift in predictable, knowledge-based plant breeding" 31 : 375-383, 2013

11 Lee HY, "Selection and characterization of a rice mutant resistant to 5-methyltryptophan" 82 : 405-408, 1991

12 Voytas DF, "Precision genome engineering and agriculture: opportunities and regulatory challenges" 12 : e1001877-, 2014

13 Shukla VK, "Precise genome modification in the crop species Zea mays using zinc-finger nucleases" 459 : 437-441, 2009

14 Kempe K, "Pollination control technologies for hybrid breeding" 27 : 417-437, 2011

15 Takagi H, "MutMap accelerates breeding of a salt-tolerant rice cultivar" 33 : 445-449, 2015

16 Holme IB, "Intragenesis and cisgenesis as alternatives to transgenic crop development" 11 : 395-407, 2013

17 Li T, "High efficiency TALEN-based gene editing produces disease-resistant rice" 30 : 390-392, 2012

18 Moore T, "Genomic imprinting in mammalian development: a parental tug-of-war" 7 : 45-49, 1991

19 Abe A, "Genome sequencing reveals gronomically important loci in rice using MutMap" 30 : 174-178, 2012

20 Yan J, "Genetic characterization and linkage disequilibrium estimation of a global maize collection using SNP markers" 4 : e8451-, 2009

21 Wu X, "Fbxl10/Kdm2b recruits polycomb repressive complex 1 to CpG islands and regulates H2A ubiquitylation" 49 : 1134-1146, 2013

22 Zhou X, "Exploiting SNPs for biallelic CRISPR mutations in the out crossing woody perennial Populus reveals 4-coumarate:CoA ligase specificity and redundancy" 208 : 298-301, 2015

23 Belhaj K, "Editing plant genomes with CRISPR/Cas9" 32 : 76-84, 2015

24 Jiang W, "Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in Arabidopsis, tobacco, sorghum and rice" 41 : e188-, 2013

25 Saze H, "DNA methylation in plants: relationship to small RNAs and histone modifications, and functions in transposon inactivation" 53 : 766-784, 2012

26 Shan Q, "Creation of fragrant rice by targeted knockout of the OsBADH2 gene using TALEN technology" 13 : 791-800, 2015

27 Baker GA, "Consumer response to GMO foods: branding, certification, and consumer characteristics" 2002

28 Kim DS, "Characterization of the altered anthranilate synthase in 5-methyltryptophan resistant rice mutants" 24 : 357-365, 2005

29 Van der Hoorn RA, "Agroinfiltration is a versatile tool that facilitates comparative analyses of Avr9/Cf-9-Induced and Avr4/Cf-4-induced necrosis" 13 : 439-446, 2000

30 Wakasa K, "A 5-methyltryptophan resistant rice mutant, MTR1, selected in tissue-culture" 74 : 49-54, 1987