Background: Dengue is the most rapidly spreading mosquito-borne viral disease in the world, including Indonesia. Dengue virus (DENV) is a small single-stranded RNA virus comprising four distinct serotypes (DENV-1, DENV-2, DENV-3, DENV-4). DENV-3 is a ...
Background: Dengue is the most rapidly spreading mosquito-borne viral disease in the world, including Indonesia. Dengue virus (DENV) is a small single-stranded RNA virus comprising four distinct serotypes (DENV-1, DENV-2, DENV-3, DENV-4). DENV-3 is a major cause of severe dengue infection in Indonesia. Currently, in several area changes in certain serotype related with severe infection. Family members are expected to take part in prevention, early detection of the morbidity and mortality associated with dengue infection and as reference source for health worker and researchers. Methods: A total of 460 patients enrolled this study. Informed consent was obtained prior to recruitment of patients enrolled into the study. During their admission to 5 hospitals and 15 primary health centers, data of characteristics and clinical information (symptoms, laboratory and severity of dengue infection) were collected during January 2012 to December 2013. The subject is patient with fever on day 1 or 2, suspected Dengue infection according to WHO criteria, and shows positive dengue NS1 and or IgM, IgG anti-dengue using a rapid screening test. The family members and health workers came to the patient`s neighborhood and observed wheter there are same symtoms in radius of 100 meters from the patient`s house. Results: From 460 patients, DENV-1 has been documented as the most frequent serotype among dengue cases (19, 34%), followed by DENV-2 (19, 13%). Spontaneous haemorrhagic manifestations occurs on 36 patients (7, 8%) of the 460 patients. Allpatients with haemorrhagic manifestations, 12 (33, 33%) and 5 (13, 8%) were caused by DENV-2, DENV-1 respectively. All subject discharge from health facility on recovery, undeveloped to DSS or death. Conclusions: Empowering family members and health worker can give an important contribution in early case detection to zero morbidity, mortality and transmission.