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      Prevalence and materno-fetal outcomes of preeclampsia/eclampsia amongst pregnant women at a teaching hospital in north-central Nigeria: a retrospective cross-sectional study

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      https://www.riss.kr/link?id=A107955770

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      다국어 초록 (Multilingual Abstract)

      Preeclampsia/eclampsia (PE/E) contributes significantly to maternal, perinatal morbidity and mortality in Nigeria. The objectives of the study were to ascertain the prevalence, materno-fetal outcomes and sociodemographic factors associated with PE/E at Nigerian Teaching Hospital from September 2014 to August 2019.
      This was a retrospective cross-sectional study that analyzed deidentified secondary data of women managed for PE/E at a teaching hospital in north-central, Nigeria. Descriptive statistics were used to determine sample characteristics and study outcome estimates. Bivariate analysis was used to test for associations between sociodemographic factors and PE/E, materno-fetal outcomes while logistic regression analysis was used to test for the magnitude of these associations. The significance level was set at P < 0.05.


      The prevalence of PE/E in this study was 3.60%. Preeclampsia was diagnosed in 3.02% of cases while eclampsia was the diagnosis in 0.58%. Case fatality rate was 3.9% and still birth rate was 10.7%. Majority of women (85.4%) did not have any maternal complication nor unfavorable outcome. Majority (67.7%), of babies weighed less than 2500 g and birth weight was the only sociodemographic factor that was significantly associated with fetal outcome (X 2 = 15.6, P < 0.001).
      The prevalence of PE/E in this study is high and is associated with high maternal and perinatal deaths. Majority of the cases of PE/E as well the fatalities occurred in women who had no formal education, unbooked and referred to the teaching hospital with worsening conditions. There is need for explorative research on community factors associated with PE/E and its outcome towards prevention and early management of cases.
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      Preeclampsia/eclampsia (PE/E) contributes significantly to maternal, perinatal morbidity and mortality in Nigeria. The objectives of the study were to ascertain the prevalence, materno-fetal outcomes and sociodemographic factors associated with PE/E a...

      Preeclampsia/eclampsia (PE/E) contributes significantly to maternal, perinatal morbidity and mortality in Nigeria. The objectives of the study were to ascertain the prevalence, materno-fetal outcomes and sociodemographic factors associated with PE/E at Nigerian Teaching Hospital from September 2014 to August 2019.
      This was a retrospective cross-sectional study that analyzed deidentified secondary data of women managed for PE/E at a teaching hospital in north-central, Nigeria. Descriptive statistics were used to determine sample characteristics and study outcome estimates. Bivariate analysis was used to test for associations between sociodemographic factors and PE/E, materno-fetal outcomes while logistic regression analysis was used to test for the magnitude of these associations. The significance level was set at P < 0.05.


      The prevalence of PE/E in this study was 3.60%. Preeclampsia was diagnosed in 3.02% of cases while eclampsia was the diagnosis in 0.58%. Case fatality rate was 3.9% and still birth rate was 10.7%. Majority of women (85.4%) did not have any maternal complication nor unfavorable outcome. Majority (67.7%), of babies weighed less than 2500 g and birth weight was the only sociodemographic factor that was significantly associated with fetal outcome (X 2 = 15.6, P < 0.001).
      The prevalence of PE/E in this study is high and is associated with high maternal and perinatal deaths. Majority of the cases of PE/E as well the fatalities occurred in women who had no formal education, unbooked and referred to the teaching hospital with worsening conditions. There is need for explorative research on community factors associated with PE/E and its outcome towards prevention and early management of cases.

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      참고문헌 (Reference)

      1 Oladapo OT, "When getting there is not enough : a nationwide cross-sectional study of 998 maternal deaths and 1451 near-misses in public tertiary hospitals in a low-income country" 123 : 928-938, 2016

      2 Kooffreh ME, "The prevalence of pre-eclampsia among pregnant women in the University of Calabar Teaching Hospital, Calabar Saudi" 3 : 133-136, 2014

      3 Ajah LO, "The fetomaternal outcome of preeclampsia with severe features and eclampsia in Abakaliki, South-East Nigeria" 10 : QC18-QC21, 2016

      4 Poon LC, "The International Federation of Gynecology and Obstetrics(FIGO)initiative on pre-eclampsia : a pragmatic guide for first-trimester screening and prevention" 145 (145): 1-33, 2019

      5 Onoh RC, "Severe preeclampsia and eclampsia : a 6-year review at the Federal Teaching Hospital, Abakaliki, Southeast Nigeria" 36 : 418-423, 2019

      6 Bilano VL, "Risk factors of preeclampsia/eclampsia and its adverse outcomes in low-and middle-income countries : a WHO secondary analysis" 9 : e91198-, 2014

      7 Osungbade KO, "Public health perspectives of preeclampsia in developing countries : implication for health system strengthening" 2011 : 481095-, 2011

      8 Olatunji AO, "Presentation and outcome of eclampsia at a Nigerian university hospital" 10 : 1-4, 2007

      9 Adamu AN, "Pregnancy outcome in women with eclampsia at a tertiary Centre in northern Nigeria" 41 : 211-219, 2012

      10 Agida ET, "Pregnancy outcome in eclamptics at the University of Abuja Teaching Hospital, Gwagwalada, Abuja : a 3 year review" 13 : 394-398, 2010

      1 Oladapo OT, "When getting there is not enough : a nationwide cross-sectional study of 998 maternal deaths and 1451 near-misses in public tertiary hospitals in a low-income country" 123 : 928-938, 2016

      2 Kooffreh ME, "The prevalence of pre-eclampsia among pregnant women in the University of Calabar Teaching Hospital, Calabar Saudi" 3 : 133-136, 2014

      3 Ajah LO, "The fetomaternal outcome of preeclampsia with severe features and eclampsia in Abakaliki, South-East Nigeria" 10 : QC18-QC21, 2016

      4 Poon LC, "The International Federation of Gynecology and Obstetrics(FIGO)initiative on pre-eclampsia : a pragmatic guide for first-trimester screening and prevention" 145 (145): 1-33, 2019

      5 Onoh RC, "Severe preeclampsia and eclampsia : a 6-year review at the Federal Teaching Hospital, Abakaliki, Southeast Nigeria" 36 : 418-423, 2019

      6 Bilano VL, "Risk factors of preeclampsia/eclampsia and its adverse outcomes in low-and middle-income countries : a WHO secondary analysis" 9 : e91198-, 2014

      7 Osungbade KO, "Public health perspectives of preeclampsia in developing countries : implication for health system strengthening" 2011 : 481095-, 2011

      8 Olatunji AO, "Presentation and outcome of eclampsia at a Nigerian university hospital" 10 : 1-4, 2007

      9 Adamu AN, "Pregnancy outcome in women with eclampsia at a tertiary Centre in northern Nigeria" 41 : 211-219, 2012

      10 Agida ET, "Pregnancy outcome in eclamptics at the University of Abuja Teaching Hospital, Gwagwalada, Abuja : a 3 year review" 13 : 394-398, 2010

      11 Tukur J, "Pattern of eclampsia in a tertiary health facility situated in a semi-rural town in northern Nigeria" 6 : 164-167, 2007

      12 Nwafor JI, "Pattern and determinants of mortality among eclamptic women that presented in the Federal Teaching Hospital, Abakaliki, southeast, Nigeria" 36 : 67-72, 2019

      13 Ade-Ojo IP, "Outcome of eclampsia at the Obafemi Awolowo University teaching hospital complex, Ile-Ife" 11 : 279-284, 2008

      14 National Population Commission(Nigeria), "Nigeria demographic and health survey 2018" National Population Commission 2019

      15 Ghulmiyyah L, "Maternal mortality from preeclampsia/eclampsia" 36 : 56-59, 2012

      16 Nwobodo EI, "Maternal mortality associated with eclampsia in Sokoto, Nigeria" 23 : 49-53, 2011

      17 Ugwu EO, "Maternal and perinatal outcome of severe pre-eclampsia in Enugu, Nigeria after introduction of magnesium sulfate" 14 : 418-421, 2011

      18 Tukur J, "Maternal and fetal outcomes after introduction of magnesium sulphate for treatment of preeclampsia and eclampsia in selected secondary facilities : a low-cost intervention" 17 : 1191-1198, 2013

      19 Griffin JB, "Interventions to reduce neonatal mortality : a mathematical model to evaluate impact of interventions in sub-Saharan Africa" 106 : 1286-1295, 2017

      20 Musa J, "Incidence and risk factors for pre-eclampsia in Jos Nigeria" 18 : 584-595, 2018

      21 Naidoo H, "Improving survival of preterm babies in low-to middle-income countries – what can we do?" 12 : 117-120, 2018

      22 World Health Organization (WHO), "Implementation of the ANC guideline and recommendations: introducing the 2016 WHO ANC model In: WHO recommendations on antenatal care for a positive pregnancy experience" WHO

      23 Singh S, "Hypertensive disorders in pregnancy among pregnant women in a Nigerian teaching hospital" 55 : 384-388, 2014

      24 Charan J, "How to calculate sample size for different study designs in medical research?" 35 : 121-126, 2013

      25 Abalos E, "Global and regional estimates of preeclampsia and eclampsia : a systematic review" 170 : 1-7, 2013

      26 Adokiye EA, "Factors influencing the prevalence of preeclampsiaeclampsia in booked and unbooked patients : 3years retrospective study in NDUTH, Okolobiri" 3 : 1-14, 2015

      27 Esike CO, "Eclampsia in rural Nigeria : the unmitigating catastrophe" 16 : 175-180, 2017

      28 Ekele BA, "Clusters of eclampsia in a Nigerian teaching hospital" 96 : 62-66, 2007

      29 Tavares Da Silva F, "Case definition and guidelines for data collection, analysis, and presentation of maternal immunization safety data" 34 : 6057-6068, 2016

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2022 평가예정 신규평가 신청대상 (신규평가)
      2021-12-01 평가 등재후보 탈락 (계속평가)
      2019-01-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
      2015-12-01 평가 등재후보 탈락 (기타)
      2015-02-06 학술지명변경 외국어명 : Journal of the Korean Society of Hypertension -> Clinical Hypertension KCI등재후보
      2015-02-06 학술지명변경 한글명 : 대한고혈압학회지 -> Clinical Hypertension
      외국어명 : Journal of the Korean Society of Hypertension -> Clinical Hypertension
      KCI등재후보
      2013-01-01 평가 등재후보학술지 유지 (기타) KCI등재후보
      2011-01-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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