生藥複合劑와 抗癌劑의 倂用投與에 관한 硏究(第3報) : Cyclophosphamide와 녹용대보탕, 오령산의 병용투여에 의한 부작용 경감 Mitigation in Toxicity of Cyclophosphamide by Combination Administration of Nokyongdaebo-Tang and Oryung-San = Studies on Combination Administration of Combined Preparation of Crude Drugs and Anti-neoplastic Drugs(Ⅲ)

다국어 초록 (Multilingual Abstract)

The studies were conducted to investigate the mitigatory effects in toxicity of cyclophosphamide through combined usage of Nokyongdaebo-Tang and Oryung-San.
The administration of Nokyongdaebo-Tang and Oryung-San recovered body weight reduced by treatment with cyclophosphamide. It was observed that renal toxicity of which scale is increase of blood urea nitrogen value and hepatotoxicity of which scale is increase of GOT and GPT when the mice was treated with cyclophosphamide were decreased by treatment with Nokyongdaebo-Tang. The number of platelet was decreased i mice which was administered cyclophosphamide, but recovered by treatment with Nokyongdaebo-Tang.