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      KCI등재

      고암모니아혈증을 동반한 전신성 염증으로 인한 당뇨병성 케톤산증 환자 치험 1례 = A Case Report of a Patient Diagnosed with Diabetic Ketoacidosis Accompanied by Hyperammonemia from Systemic Inflammation

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      https://www.riss.kr/link?id=A108161753

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      다국어 초록 (Multilingual Abstract)

      A 42-year-old male patient with prolonged throat pain and discomfort, dry mouth, and general weakness and recently diagnosed with tonsillitis, pulmonary embolism, and venous thrombosis was admitted to the internal Korean medicine department. A sudden ...

      A 42-year-old male patient with prolonged throat pain and discomfort, dry mouth, and general weakness and recently diagnosed with tonsillitis, pulmonary embolism, and venous thrombosis was admitted to the internal Korean medicine department. A sudden onset of diabetic ketoacidosis with hyperammonemia was diagnosed on the second day of treatment. During admission, the patient received insulin therapy, hydration, and traditional Korean medicine treatment, including herbal medicine. Subjective symptom change was evaluated daily and blood glucose level checked five times per day. At discharge, the patient’s fasting and postprandial blood sugar levels were adequate. After an additional two weeks of herbal treatment, the symptoms were significantly ameliorated. Thus, having been admitted with dysregulated glucose metabolism leading to a hyperglycemic crisis after a series of inflammatory events, the patient showed symptomatic improvements and decreased blood glucose after 18 days of hospitalization and treatment.

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      참고문헌 (Reference)

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      2 Liu HJ, "α-Asarone Attenuates Cognitive Deficit in a Pilocarpine-Induced Status Epilepticus Rat Model via a Decrease in the Nuclear Factor-κB Activation and Reduction in Microglia Neuroinflammation" 8 : 661-, 2017

      3 Hwang SH, "Xanthium strumarium as an Inhibitor of α-Glucosidase, Protein Tyrosine Phosphatase 1β, Protein Glycation and ABTS⁺ for Diabetic and Its Complication" 21 (21): 1241-, 2016

      4 Forget P, "What is the normal value of the neutrophil-to-lymphocyte ratio?" 10 (10): 12-, 2017

      5 Ohara N, "Type 1 Diabetes Mellitus and Pernicious Anemia in an Elderly Japanese Patient : A Case Report and Literature Review" 54 (54): 2361-2365, 2015

      6 Pribiag H, "TNF-α downregulates inhibitory neurotransmission through protein phosphatase 1-dependent trafficking of GABA(A)receptors" 33 (33): 15879-15893, 2013

      7 Nationwide College of Korean Medicine Department of Sasang Constitution, "Revised and Enlarged Sasang Constitutional Medicine" Jipmoondang 292-294, 2016

      8 Stentz FB, "Proinflammatory cytokines, markers of cardiovascular risks, oxidative stress, and lipid peroxidation in patients with hyperglycemic crises" 53 (53): 2079-2086, 2004

      9 Chaudhuri A, "Oxidative stress and inflammation in hyperglycemic crises and resolution with insulin : implications for 2he acute and chronic complications of hyperglycemia" 26 (26): 257-258, 2012

      10 Manappallil RG, "Noncirrhotic hyperammonemia in a newly diagnosed diabetic patient presenting in diabetic ketoacidosis" 5 (5): 217-218, 2019

      1 김도훈 ; 백유상, "황제내경의 오수혈 임상 활용 연구 – 사용 빈도와 선혈을 중심으로" 경락경혈학회 37 (37): 276-283, 2020

      2 Liu HJ, "α-Asarone Attenuates Cognitive Deficit in a Pilocarpine-Induced Status Epilepticus Rat Model via a Decrease in the Nuclear Factor-κB Activation and Reduction in Microglia Neuroinflammation" 8 : 661-, 2017

      3 Hwang SH, "Xanthium strumarium as an Inhibitor of α-Glucosidase, Protein Tyrosine Phosphatase 1β, Protein Glycation and ABTS⁺ for Diabetic and Its Complication" 21 (21): 1241-, 2016

      4 Forget P, "What is the normal value of the neutrophil-to-lymphocyte ratio?" 10 (10): 12-, 2017

      5 Ohara N, "Type 1 Diabetes Mellitus and Pernicious Anemia in an Elderly Japanese Patient : A Case Report and Literature Review" 54 (54): 2361-2365, 2015

      6 Pribiag H, "TNF-α downregulates inhibitory neurotransmission through protein phosphatase 1-dependent trafficking of GABA(A)receptors" 33 (33): 15879-15893, 2013

      7 Nationwide College of Korean Medicine Department of Sasang Constitution, "Revised and Enlarged Sasang Constitutional Medicine" Jipmoondang 292-294, 2016

      8 Stentz FB, "Proinflammatory cytokines, markers of cardiovascular risks, oxidative stress, and lipid peroxidation in patients with hyperglycemic crises" 53 (53): 2079-2086, 2004

      9 Chaudhuri A, "Oxidative stress and inflammation in hyperglycemic crises and resolution with insulin : implications for 2he acute and chronic complications of hyperglycemia" 26 (26): 257-258, 2012

      10 Manappallil RG, "Noncirrhotic hyperammonemia in a newly diagnosed diabetic patient presenting in diabetic ketoacidosis" 5 (5): 217-218, 2019

      11 Hawkes ND, "Non-hepatic hyperammonaemia : an important, potentially reversible cause of encephalopathy" 77 (77): 717-722, 2001

      12 Khodabandehloo H, "Molecular and cellular mechanisms linking inflammation to insulin resistance and β-cell dysfunction" 167 (167): 228-256, 2016

      13 Ahn YK, "Meridian Study Series (Gyeonghyeolhak -Chongseo)" Seongbo-sa; 281-432, 2006

      14 Xu E, "Intra-islet insulin suppresses glucagon release via GABA-GABAA receptor system" 3 (3): 47-58, 2006

      15 Lee HJ, "Hyperglycemic emergencies associated with COVID-19 vaccination : a case series and discussion" 5 (5): bvab141-, 2021

      16 Kitabchi AE, "Hyperglycemic crises in adult patients with diabetes" 32 (32): 1335-1343, 2009

      17 Clay AS, "Hyperammonemia in the ICU" 132 (132): 1368-1378, 2007

      18 Chen JS, "Ginkgo biloba extract reduces high-glucose-induced endothelial adhesion by inhibiting the redox-dependent interleukin-6pathways" 11 (11): 49-, 2012

      19 Soltani N, "GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes" 108 (108): 11692-11697, 2011

      20 Wang Y, "Formononetin attenuates IL-1β-induced apoptosis and NF-κB activation in INS-1 cells" 17 (17): 10052-10064, 2012

      21 Dula SB, "Evidence that low-grade systemic inflammation can induce islet dysfunction as measured by impaired calcium handling" 48 (48): 133-142, 2010

      22 Cho DH, "Effective Management of Diabetic Ketoacidosis" 19 (19): 208-213, 2018

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      24 Heo J, "Donguibogam" Namsandang 74-507, 1996

      25 Won DP, "Dongui Sasang Sinpyeon" Jeongdam 188-, 2002

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      27 Yang JZ, "Complete Compendium of Acupuncture and Moxibustion(Chimgudaeseong)" Daeseongmunhwa-sa 809-857, 1996

      28 Yun Jae Shin ; Dae In Kim ; Dong Won Lee ; Beung Kwan Jeon ; Jung Geun Ji ; Jung Ah Lim ; Young Jung Cho ; Hong Woo Nam, "Clinical and Biochemical Characteristics of Elderly Patients With Hyperglycemic Emergency State at a Single Institution" 대한노인병학회 20 (20): 185-189, 2016

      29 Samuel SM, "COVID-19 Vaccines and Hyperglycemia-Is There a Need for Postvaccination Surveillance?" 10 (10): 454-, 2022

      30 Huang GS, "Boncho Gujin" Tree and Soil Publising 391-962, 1999

      31 Banin RM, "Beneficial effects of Ginkgo biloba extract on insulin signaling cascade, dyslipidemia, and body adiposity of diet-induced obese rats" 47 (47): 780-788, 2014

      32 Ha Na Yoon ; Min Young Lee ; 김진규 ; 서홍원 ; 임순성, "Aldose Reductase Inhibitory Compounds from Xanthium strumarium" 대한약학회 36 (36): 1090-1095, 2013

      33 Ghanim H, "Acute modulation of toll-like receptors by insulin" 31 (31): 1827-1831, 2008

      34 Ha JH, "4-Hydroxybenzaldehyde from Gastrodiaelata B1. is active in the antioxidation and GABAergic neuromodulation of the rat brain" 73 (73): 329-333, 2000

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2022 평가예정 재인증평가 신청대상 (재인증)
      2019-01-01 평가 등재학술지 유지 (계속평가) KCI등재
      2016-01-01 평가 등재학술지 선정 (계속평가) KCI등재
      2015-12-01 평가 등재후보로 하락 (기타) KCI등재후보
      2011-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2009-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2006-02-09 학술지명변경 외국어명 : THE KOREAN SOCIETY FOR ORIENTAL INTERNAL MEDICINE -> The Journal of Korean Oriental Internal Medicine KCI등재
      2006-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      2005-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2003-01-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.67 0.67 0.61
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.56 0.5 0.653 0.03
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