Few case reports and clinical series exist on pregnant women infected with SARS‐CoV‐2 who delivered.
To review the available information on mode of delivery, vertical/peripartum transmission, and neonatal outcome in pregnant women infected with SA...
Few case reports and clinical series exist on pregnant women infected with SARS‐CoV‐2 who delivered.
To review the available information on mode of delivery, vertical/peripartum transmission, and neonatal outcome in pregnant women infected with SARS‐CoV‐2.
Combination of the following key words: COVID‐19, SARS‐CoV‐2, and pregnancy in Embase and PubMed databases.
Papers reporting cases of women infected with SARS‐CoV‐2 who delivered.
The following was extracted: author; country; number of women; study design; gestational age at delivery; selected clinical maternal data; mode of delivery; selected neonatal outcomes.
In the 13 studies included, vaginal delivery was reported in 6 cases (9.4%; 95% CI, 3.5–19.3). Indication for cesarean delivery was worsening of maternal conditions in 31 cases (48.4%; 95% CI, 35.8–61.3). Two newborns testing positive for SARS‐CoV‐2 by real‐time RT‐PCR assay were reported. In three neonates, SARS‐CoV‐2 IgG and IgM levels were elevated but the RT‐PCR test was negative.
The rate of vertical or peripartum transmission of SARS‐CoV‐2 is low, if any, for cesarean delivery; no data are available for vaginal delivery. Low frequency of spontaneous preterm birth and general favorable immediate neonatal outcome are reassuring.
The rate of vertical or peripartum transmission of SARS‐CoV‐2 is low, if any, for cesarean delivery; no data are available for vaginal delivery.