A case of metastatic squamous cell carcinoma in the skin = A case of metastatic squamous cell carcinoma in the skin

다국어 초록 (Multilingual Abstract)

Squamous cell carcinoma(SCC) is the second most common form of skin cancer. It is usually found on sun-exposed areas such as head, neck, lips, arms, etc. It presents as a firm, flesh-colored or erythematous, keratotic papule or plaque and it may also be ulcerative, nodular or verrucous. Metastatic SCC usually presents as well-demarcated painless nodules and may be mistaken for epidermal cyst, fibroma, lipomas or other benign conditions. It also resembles the primary SCC. Histopathologic examination is necessary to confirm the diagnosis. The hallmark of invasive SCC is the extension of atypical keratinocytes beyond the basement membrane and into the dermis. Grade of differentiation is associated with the grade of keratinization. A 77-years-old man was consulted for right 1st finger’s ulceration with bleeding during admission in hemato-oncology department. The lesion was a 1.5x1.5cm sized round ulcerative patch and it’s onset was several months ago. A punch biopsy specimen showed proliferation of atypical keratinocytes in the whole epidermis and invasion of dermis, which means SCC. In the patient’s past history, he had lung cancer with liver, bone metastasis and it’s subtype was SCC. We think that the finger’s lesion was caused by metastasis of the lung cancer.