1 Collins, P. L., "Viral and host factors in human respiratory syncytial virus pathogenesis" J. Virol 82 : 2040 ~ 2055 -, 2008
2 Huang, S., "Upregulation of TLR7 and TLR3 gene expression in the lung of respiratory syncytial virus infected mice" Wei Sheng Wu Xue Bao 49 : 239 ~ 245 -, 2009
3 Vermeulen, L., "Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)" EMBO J 22 : 1313 ~ 1324 -, 2003
4 Conzelmann, K. K., "Transcriptional activation of alpha/ beta interferon genes: interference by nonsegmented negative-strand RNA viruses" J. Virol 79 : 5241 ~ 5248 -, 2005
5 Inoue, Y., "Toll-Like Receptor 2 as a Functional Receptor to Respiratory Syncytial Virus" J. Allergy Clin. Immunol 117 : S210 ~ -, 2006
6 Ehl, S., "The role of Toll-like receptor 4 versus interleukin-12 in immunity to respiratory syncytial virus" Eur. J. Immunol 34 : 1146 ~ 1153 -, 2004
7 Dejardin, E., "The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways" Immunity 17 : 525 ~ 535 -, 2002
8 Segovia, J., "TLR2/MyD88/NF-kappaB pathway, reactive oxygen species, potassium efflux activates NLRP3/ ASC inflammasome during respiratory syncytial virus infection" PLoS One 7 : e29695 ~ -, 2012
9 Puthothu, B., "TLR-4 and CD14 polymorphisms in respiratory syncytial virus associated disease" Dis. Markers 22 : 303 ~ 308 -, 2006
10 Wu, B., "Structural basis for dsRNA recognition, filament formation, and antiviral signal activation by MDA5" Cell 152 : 276 ~ 289 -, 2013
1 Collins, P. L., "Viral and host factors in human respiratory syncytial virus pathogenesis" J. Virol 82 : 2040 ~ 2055 -, 2008
2 Huang, S., "Upregulation of TLR7 and TLR3 gene expression in the lung of respiratory syncytial virus infected mice" Wei Sheng Wu Xue Bao 49 : 239 ~ 245 -, 2009
3 Vermeulen, L., "Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)" EMBO J 22 : 1313 ~ 1324 -, 2003
4 Conzelmann, K. K., "Transcriptional activation of alpha/ beta interferon genes: interference by nonsegmented negative-strand RNA viruses" J. Virol 79 : 5241 ~ 5248 -, 2005
5 Inoue, Y., "Toll-Like Receptor 2 as a Functional Receptor to Respiratory Syncytial Virus" J. Allergy Clin. Immunol 117 : S210 ~ -, 2006
6 Ehl, S., "The role of Toll-like receptor 4 versus interleukin-12 in immunity to respiratory syncytial virus" Eur. J. Immunol 34 : 1146 ~ 1153 -, 2004
7 Dejardin, E., "The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways" Immunity 17 : 525 ~ 535 -, 2002
8 Segovia, J., "TLR2/MyD88/NF-kappaB pathway, reactive oxygen species, potassium efflux activates NLRP3/ ASC inflammasome during respiratory syncytial virus infection" PLoS One 7 : e29695 ~ -, 2012
9 Puthothu, B., "TLR-4 and CD14 polymorphisms in respiratory syncytial virus associated disease" Dis. Markers 22 : 303 ~ 308 -, 2006
10 Wu, B., "Structural basis for dsRNA recognition, filament formation, and antiviral signal activation by MDA5" Cell 152 : 276 ~ 289 -, 2013
11 Ramaswamy, M., "Specific inhibition of type I interferon signal transduction by respiratory syncytial virus" Am. J. Respir. Cell. Mol. Biol 30 : 893 ~ 900 -, 2004
12 Shingai, M., "Soluble G protein of respiratory syncytial virus inhibits Toll-like receptor 3/4-mediated IFN-beta induction" Int. Immunol 20 : 1169 ~ 1180 -, 2008
13 Marr, N., "Role of human TLR4 in respiratory syncytial virus-induced NF-κB activation, viral entry and replication" Innate. Immun 18 : 856 ~ 865 -, 2012
14 Ventre, K, "Ribavirin for respiratory syncytial virus infection of the lower respiratory tract in infants and young children" Cochrane Database Syst. Rev, 2007
15 Liu, P., "Retinoic Acid-Inducible Gene I Mediates Early Antiviral Response and Toll-Like Receptor 3 Expression in Respiratory Syncytial Virus-Infected Airway Epithelial Cells" J. Virol 81 : 1401 ~ 1411, 2007
16 Fulginiti, V. A., "Respiratory virus immunization. I. A field trial of two inactivated respiratory virus vaccines; an aqueous trivalent parainfluenza virus vaccine and an alum-precipitated respiratory syncytial virus vaccine" Am. J. Epidemiol 89 : 435 ~ 448 -, 1969
17 Yoboua, F., "Respiratory syncytial virus-mediated NF-kappa B p65 phosphorylation at serine 536 is dependent on RIG-I, TRAF6, and IKK beta" J. Virol 84 : 7267 ~ 7277 -, 2010
18 Crowe, J. E., Jr., "Respiratory syncytial virus vaccine development" Vaccine 20 (Suppl 1) : S32 ~ S37 -, 2001
19 Lo, M. S., "Respiratory syncytial virus nonstructural proteins NS1 and NS2 mediate inhibition of Stat2 expression and alpha/beta interferon responsiveness" J. Virol 79 : 9315 ~ 9319 -, 2005
20 Takeuchi, R, "Respiratory syncytial virus infection of human alveolar epithelial cells enhances interferon regulatory factor 1 and interleukin-1beta-convertInnate immune recognition of respiratory syncytial virus infection Tae Hoon Kim and Heung Kyu Lee http://bmbreports.org BMB Reports 191 ing enzyme gene expression but does not cause apoptosis" J. Virol 72 : 4498 ~ 4502 -, 1998
21 Dou, Y., "Respiratory syncytial virus infection induces higher Toll-like receptor-3 expression and TNF-alpha production than human metapneumovirus infection" PLoS One 8 : e73488 ~ -, 2013
22 Jamaluddin, M., "Respiratory syncytial virus infection induces a reactive oxygen species-MSK1-phospho-Ser-276 RelA pathway required for cytokine expression" J. Virol 83 : 10605 ~ 10615 -, 2009
23 Vissers, M., "Respiratory syncytial virus infection augments NOD2 signaling in an IFN-beta-dependent manner in human primary cells" Eur. J. Immunol 42 : 2727 ~ 2735 -, 2012
24 Liu, P., "Respiratory syncytial virus induces RelA release from cytoplasmic 100-kDa NF-kappa B2 complexes via a novel retinoic acid-inducible gene-I{middle dot}NF- kappa B-inducing kinase signaling pathway" J. Biol. Chem 283 : 23169 ~ 23178 -, 2008
25 Murawski, M. R., "Respiratory syncytial virus activates innate immunity through Toll-like receptor 2" J. Virol 83 : 1492 ~ 1500 -, 2009
26 Connors, M., "Respiratory syncytial virus (RSV) F, G, M2 (22K), and N proteins each induce resistance to RSV challenge, but resistance induced by M2 and N proteins is relatively short-lived" J. Virol 65 : 1634 ~ 1637 -, 1991
27 Lukacs, N. W., "Respiratory Virus-Induced TLR7 Activation Controls IL-17-Associated Increased Mucus via IL-23 Regulation" J. Immunol 185 : 2231 ~ 2239 -, 2010
28 Haeberle, H. A., "Respiratory Syncytial Virus-Induced Activation of Nuclear Factor-κB in the Lung Involves Alveolar Macrophages and Toll-Like Receptor 4-Dependent Pathways" J. Infect. Dis 186 : 1199 ~ 1206 -, 2002
29 Monick, M. M., "Respiratory Syncytial Virus Up-regulates TLR4 and Sensitizes Airway Epithelial Cells to Endotoxin" J. Biol. Chem 278 : 53035 ~ 53044 -, 2003
30 Groskreutz, D. J., "Respiratory Syncytial Virus Induces TLR3 Protein and Protein Kinase R, Leading to Increased Double- Stranded RNA Responsiveness in Airway Epithelial Cells" J. Immunol 176 : 1733 ~ 1740 -, 2006
31 Blount, R. E., Jr, "Recovery of cytopathogenic agent from chimpanzees with coryza" Proc. Soc. Exp. Biol. Med 92 : 544 ~ 549 -, 1956
32 Chanock, R., "Recovery from infants with respiratory illness of a virus related to chimpanzee coryza agent (CCA). II. Epidemiologic aspects of infection in infants and young children" Am. J. Hyg 66 : 291 ~ 300 -, 1957
33 Chanock, R., "Recovery from infants with respiratory illness of a virus related to chimpanzee coryza agent (CCA). I. Isolation, properties and characterization" Am. J. Hyg 66 : 281 ~ 290 -, 1957
34 Pichlmair, A., "RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates" Science 314 : 997 ~ 1001 -, 2006
35 Rehwinkel, J., "RIG-I detects viral genomic RNA during negative-strand RNA virus infection" Cell 140 : 397 ~ 408 -, 2010
36 Haynes, L. M., "Progress and challenges in RSV prophylaxis and vaccine development" J. Infect. Dis 208 (Suppl 3) : S177 ~ S183 -, 2013
37 Davidson, S., "Plasmacytoid dendritic cells promote host defense against acute pneumovirus infection via the TLR7-MyD88-dependent signaling pathway" J. Immunol 186 : 5938 ~ 5948 -, 2011
38 Sasaki, C. Y., "Phosphorylation of RelA/p65 on serine 536 defines an I{kappa}B{alpha}-independent NF-{kappa}B pathway" J. Biol. Chem 280 : 34538 ~ 34547 -, 2005
39 Zhong, H., "Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300" Mol. Cell 1 : 661 ~ 671 -, 1998
40 Arnold, R., "Peroxisome proliferator- activated receptor-gamma agonists inhibit the replication of respiratory syncytial virus (RSV) in human lung epithelial cells" Virology 350 : 335 ~ 346 -, 2006
41 Kurt-Jones, E. A., "Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus" Nat. Immunol 1 : 398 ~ 401 -, 2000
42 Kumar, H., "Pathogen recognition by the innate immune system" Int. Rev. Immunol 30 : 16 ~ 34 -, 2011
43 Xiao, G., "NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100" Mol. Cell 7 : 401 ~ 409 -, 2001
44 Bhoj, V. G., "MAVS and MyD88 are essential for innate immunity but not cytotoxic T lymphocyte response against respiratory syncytial virus" Proc. Natl. Acad. Sci. U. S. A 105 : 14046 ~ 14051 -, 2008
45 Haynes, L. M., "Involvement of toll-like receptor 4 in innate immunity to respiratory syncytial virus" J. Virol 75 : 10730 ~ 10737 -, 2001
46 Schlender, J., "Inhibition of Toll-Like Receptor 7- and 9-Mediated Alpha/Beta Interferon Production in Human Plasmacytoid Dendritic Cells by Respiratory Syncytial Virus and Measles Virus" J. Virol 79 : 5507 ~ 5515 -, 2005
47 Pang, I. K., "Inflammasomes as mediators of immunity against influenza virus" Trends Immunol 32 : 34 ~ 41 -, 2011
48 Xiao, G., "Induction of p100 processing by NF-kappaB-inducing kinase involves docking IkappaB kinase alpha (IKKalpha) to p100 and IKKalpha-mediated phosphorylation" J. Biol. Chem 279 : 30099 ~ 30105 -, 2004
49 Gagro, A., "Increased Toll-like receptor 4 expression in infants with respiratory syncytial virus bronchiolitis" Clin. Exp. Immunol 135 : 267 ~ 272 -, 2004
50 Walsh, E. E., "Immunization with glycoprotein subunits of respiratory syncytial virus to protect cotton rats against viral infection" J. Infect. Dis 155 : 1198 ~ 1204 -, 1987
51 Demoor, T., "IPS-1 signaling has a nonredundant role in mediating antiviral responses and the clearance of respiratory syncytial virus" J. Immunol 189 : 5942 ~ 5953 -, 2012
52 Triantafilou, K., "Human respiratory syncytial virus viroporin SH: a viral recognition pathway used by the host to signal inflammasome activation" Thorax 68 : 66 ~ 75 -, 2013
53 Inohara, N., "Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease" J. Biol. Chem 278 : 5509 ~ 5512 -, 2003
54 Scagnolari, C., "Gene expression of nucleic acid-sensing pattern recognition receptors in children hospitalized for respiratory syncytial virus- associated acute bronchiolitis" Clin. Vaccine Immunol 16 : 816 ~ 823 -, 2009
55 Chen, L. F., "F-kappaB RelA phosphorylation regulates RelA acetylation" Mol. Cell. Biol 25 : 7966 ~ 7975 -, 2005
56 Phipps, S., "Eosinophils contribute to innate antiviral immunity and promote clearance of respiratory syncytial virus" Blood 110 : 1578 ~ 1586 -, 2007
57 Loo, Y. M., "Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity" J. Virol 82 : 335 ~ 345 -, 2008
58 Rudd, B. D., "Differential Role for TLR3 in Respiratory Syncytial Virus-Induced Chemokine Expression" J. Virol 79 : 3350 ~ 3357 -, 2005
59 Rudd, B. D., "Deletion of TLR3 Alters the Pulmonary Immune Environment and Mucus Production during Respiratory Syncytial Virus Infection" J. Immunol 176 : 1937 ~ 1942 -, 2006
60 장준, "Current progress on development of respiratory syncytial virus vaccine" BMB Reports 44 (4) : 232 ~ 237, 2011
61 Paulus, S. C., "Common human Toll-like receptor 4 polymorphisms-Role in susceptibility to respiratory syncytial virus infection and functional immunological relevance" Clin. Immunol 123 : 252 ~ 257 -, 2007
62 Zandi, E., "Bridging the gap: composition, regulation, and physiological function of the IkappaB kinase complex" Mol. Cell Biol 19 : 4547 ~ 4551 -, 1999
63 Marr, N., "Attenuation of Respiratory Syncytial Virus-Induced and RIG-I-Dependent Type I IFN Responses in Human Neonates and Very Young Children" J. Immunol 192 : 948 ~ 957 -, 2014
64 Awomoyi, A. A., "Association of TLR4 polymorphisms with symptomatic respiratory syncytial virus infection in high-risk infants and young children" J. Immunol 179 : 3171 ~ 3177 -, 2007
65 Tal, G., "Association between common Toll-like receptor 4 mutations and severe respiratory syncytial virus disease" J. Infect. Dis 189 : 2057 ~ 2063 -, 2004
66 Sabbah, A., "Activation of innate immune antiviral responses by Nod2" Nat. Immunol 10 : 1073 ~ 1080 -, 2009
67 Hornung, V., "5'-Triphosphate RNA is the ligand for RIG-I" Science 314 : 994 ~ 997 -, 2006