Management of Pregnancy Complicated with Thrombocytopenia

다국어 초록 (Multilingual Abstract)

It is not rare to diagnose thrombocytopenia during pregnancy as a result of increased awareness by routine complete blood count.
We can see mild or severe thrombocytopenia even in normal pregnant women without a history of immune thrombocytopenic purpura(ITP) or other blood dyscrasia before pregnancy.
There are close relationships between the thrombocytopenia and not Dual physiologic changes during pregnancy which are expressed with the short platelet life-span, the activation of fibrinolytic function, and the tendency of thrombi formation by the activation of blood coagulation system. Such changes, during pregnancy, induce hematological disorders, or make worse already-existing blood dyscrasias.
It is well known that there are many causes of thrombocytopenia occurring from various medical conditions, and during pregnancy.
I will review here our 5-year experiences of the management including corticosteroids therapy, intravenous gamma globulin, platelet-rich plasma transfusion and plasmapheresis and, particularly, mode of delivery of the pregnant patient with pregnancy-associated thrombocytopenia, severe preeclampsia(79 case- and the HELLP syndrome(9 cases), and immune thrombocytopenic purpura(23 cases).