연령증가에 따른 경계성고혈압 남성의 운동 시 혈압상승 기전 = Physiological Mechanism of Exgerated Blood Pressure on Static Handgrip Exercise of Prehypertension Men in Increasing Age

다국어 초록 (Multilingual Abstract)

Previous studies suggested that the exercise pressor reflex (EPR) plays an important role to regulate thecardiovascular responses during static exercise. However, the effects of the EPR on the cardiovascular responses toexercise have not been studied between young and middle aged prehypertensive men. Therefore, this study was toexamine the cardiovascular responses in prehypertensive men between static handgrip exercise and post-exercise muscleischemia (PEMI). Thirty subjects (15 young aged prehypertension: YAP and 15 middle aged prehypertension: MP)were recruited in this study. The maximum voluntary contraction (MVC) was obtained using a handgrip device in allsubjects. Each subject performed static isometric handgrip exercise at 50% MVC for 2 min followed by 2 min ofPEMI by inflating a cuff on the upper arm to 40 mmHg of resting systolic blood pressure (SBPrest). All subjects werecontinuously instrumented to measure cardiovascular variables that blood pressure (SBP, DBP), stroke volume (SV), heartrate (HR), cardiac output (CO), total vascular conductance (TVC) throughout the experiment by using of the Finometer device.
From the baseline values, the increased in mean arterial pressure (MAP) was no significantly different between YAP and MPduring SHE (YAP: Δ53 vs. MP: Δ48 mmHg) and PEMI (YAP: Δ36 vs. MP: Δ35 mmHg). In static handgrip exercise, theincrease in cardiac output was significantly higher (YAP: Δ2.1 vs. MP: Δ0.8 L/min) than MP group, and in PEMI, totalvascular conductance was significantly less decreased (YAP: Δ-21.7 vs. MP: Δ-12.9 ml/min/mmHg) than YAP group. Thisstudy indicates the reflex pressor response seen during static handgrip exercise and PEMI in men and may help toexplain the neural mechanism where by prehypertensive men display excessive blood pressure response during statichandgrip exercise and PEMI.

참고문헌 (Reference)

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