Conclusively we observed that the Pd(0)-catalyzed coupling reaction of ρ-bromocalix[4]arene tetrahexyl ether 3 with arylboronic acids having various functional groups, e.g. even a sterically hindered ortho substituent can be used as a general method ...
Conclusively we observed that the Pd(0)-catalyzed coupling reaction of ρ-bromocalix[4]arene tetrahexyl ether 3 with arylboronic acids having various functional groups, e.g. even a sterically hindered ortho substituent can be used as a general method to get a calix[4]arene derivative having conestructured rigid deep-cavity. Molecular recognition studies and further functionalizations of obtained hosts are in progress.