항암화학요법을 받는 암환자의 말초신경병증과 우울 = Chemotherapy-induced Peripheral Neuropathy and Depression in Cancer Patients

다국어 초록 (Multilingual Abstract)

University, Seoul, Korea Purpose: The purpose of this study was to assess chemotherapy induced peripheral neuropathy (CIPN) and to examine the relationship between CIPN and depression. Methods: A purposive sample of 105 patients treated with chemotherapy were recruited in the cross-sectional survey design. Data were collected using self-report questionnaires. The instruments used were the Chemotherapy Induced Peripheral Neuropathy Assessment Tool (CIPNAT) and Hospital Anxiety Depression Scale (HADS). Results: The most frequent suffering symptom of CIPN was ‘tingling feeling in the hand and foot’. Of the motor symptoms, ‘muscle weakness’ was the most frequent symptom and ‘muscle or joint aches’ was the strongest suffering symptom of CIPN. The mean score for suffering of CIPN was 4.1. The mean score was 1.04 for depression and the prevalence was 48.5%. CIPN was significantly positively correlated with depression (r=.38, p<.001). The result of simple regression analysis revealed that CIPN was predictive of depression (R2=.136, p<.001). Conclusion: Based on the findings of this study, nursing intervention programs focusing on CIPN management and alleviating

참고문헌 (Reference)

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7 Gedge D. Rosson, "Chemotherapy-Induced Neuropathy" Elsevier BV 23 (23): 637-649, 2006