트레드밀 운동 강도와 기간이 흰쥐의 흑질에서 tyrosine hydroxylase 발현에 미치는 영향 = The Effect of Intensity-, Dependence- Treadmill Exercise on TH (tyrosine hydroxylase) Expression in the Substantia Nigra of Rats

다국어 초록 (Multilingual Abstract)

In the present study, the effect of intensity-, duration-dependence of treadmill exercise on TH expression in the substantia nigra of rats was investigated via immunohistochemistry. In an intensity-treadmill exercise, animals were divided into four groups: the control group, the mild-exercise group, the moderate-exercise group, and the severe-exercise group(n=10 in each group). In a duration-treadmill exercise, animals were divided into six groups: the control group, the 1-day-exercise group, the 3-days-exercise group, the 7-days-exercise group, the 14-days-exercise group, the 28-days-exercise group(n=10 in each group).
The results are as follows:
1. TH-positive cells expression in the substantia nigra appears to have increased from treadmill exercise with intensity, until moderate intensity. However, no significant difference observed between the moderate-exercise group and the severe-exercise group.
2. TH-positive cells expression in the substantia nigra appears to have reached the maximum level on the 7th days of exercise, after which it gradually decreased. Also, no significant difference observed between the 28th day-exercise group and the control group.
These results showed that intensity-, duration-dependence treadmill exercise on changes of TH expression represent the physiological response and adaptation of exercise in the brain as a homeostasis.

목차 (Table of Contents)

• ABSTRACT
• Ⅰ. 서론
• Ⅱ. 연구방법
• Ⅲ. 연구결과
• Ⅳ. 논의
• Ⅴ. 결론
• 참고문헌