혈소판 풍부 혈장의 주사치료

국문 초록 (Abstract)

혈소판 풍부 혈장(platelet-rich plasma)은 자가혈액에서 혈소판을 추출한 농축액이며, 정상 혈액보다 많은 성장인자를 포함하여 손상된 조직 치유에 도움이 된다. 이러한 근거를 바탕으로 혈소판 풍부 혈장은 다양한 근골격계 손상 및 질환에서 사용되는 치료 방법 중 하나이며 사용 시도가 증가하고 있지만 아직까지 과학적 근거제시가 부족한 상황이며 수준 높은 임상시험을 통한 결과보고가 적은 것이 현실이다. 또한 혈소판 풍부 혈장은 4Ds (Drug [platelet-rich plasma], Delivery [application method], Donor [patients], Disease [stage of disease])에 의한 연구 간 차이로 다양한 결과들이 나오게 되었으며, 혈소판 풍부 혈장의 주사치료에 대한 효용성에 성급한 결론을 내리는 것은 아직 이르다. 질환의 부위, 종류, 급성 또는 만성 질환 정도에 따라 최적의 적용 시기나 적용 방법이 달라야 하며, 이에 대한 혈소판 풍부 혈장의 제조상의 표준화를 이루고 각각의 분석 및 연구가 필요하다.

다국어 초록 (Multilingual Abstract)

Platelet-rich plasma (PRP) supplies numerous growth factors from concentrated platelets required to promote the healing process of injured or degenerated tissue. PRP is already a popular option to treat a variety of musculoskeletal injuries and diseases, even though the precise mechanism of action is not completely understood. Varying outcomes, from favorable to poor, after PRP injection may arise from interstudy differences with respect to 4Ds (Drug [PRP], Delivery [application method], Donor [patients], and Disease [stage of rotator cuff disease]). In addition, there is no standard treatment regimen (injection location, number, interval, volume). Therefore, precise outcome measures as well as long-term follow-up are required to accurately evaluate the efficacy.

목차 (Table of Contents)

• 서론
• CLINICAL APPLICATION OF PLATELET-RICH PLASMA INJECTION
• 결론
• REFERENCES

참고문헌 (Reference)

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