Dermoscopic features of large cell acanthoma = Dermoscopic features of large cell acanthoma

다국어 초록 (Multilingual Abstract)

Background: Large cell acanthoma (LCA) is a sharply demarcated epidermal lesion composed of large keratinocytes. There is a lack of consensus regarding whether it represents a distinct benign entity or a variant of other diseases. LCA commonly mimics other lesions such as solar lentigo and seborrheic keratosis. Dermoscopy is a noninvasive method of diagnosis which allows the visualization of pigmented and vascular structures. There was no previous study focusing on dermoscopic features of LCA.
Objectives: To investigate characteristic dermoscopic patterns of LCA, and to find distinctive features that can differentiate them from other lesions.
Methods: Clinical features and dermoscopic patterns were evaluated in 13 patients, histologically diagnosed as LCA.
Results: The patients were between 48 and 94 years of age with mean age of 68.1 years. The common site of occurrence was leg. The dermoscopic features showed yellow opaque homogeneous area, gray and brown dots and globules, moth-eaten border, short white streaks, and pseudonetwork (100%, 69.2%, 46.2%, 38.5%, and 30.8%, respectively). Otherwise, milia-like cyst and white-to-yellow surface scale (23.1% and 7.7%, respectively) were uncommon findings.
Conclusion: Dermoscopy provides valuable information for the diagnosis of LCA and can be useful in the differential diagnosis of other pigmented skin lesions.