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      Newly Diagnosed Sarcopenia and Alzheimer’s Disease in an Older Patient With Chronic Inflammation

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      https://www.riss.kr/link?id=A106097739

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      다국어 초록 (Multilingual Abstract)

      A 78-year-old man presented with the aggravation of weakness in the lower extremities, gait disturbance, and cognitive impairment. He was diagnosed with sarcopenia, distal sen-sorimotor polyneuropathy, and Alzheimer’s disease. Low-grade chronic elev...

      A 78-year-old man presented with the aggravation of weakness in the lower extremities, gait disturbance, and cognitive impairment. He was diagnosed with sarcopenia, distal sen-sorimotor polyneuropathy, and Alzheimer’s disease. Low-grade chronic elevation of inflam-matory markers was also revealed. We assumed that chronic low-grade inflammation with aging, also called “inflammaging,” contributed to the development of multiple comorbidi-ties. After multidisciplinary treatment and comprehensive rehabilitation, he could ambu-late again with minimal to moderate assistance. Various age-related disorders should be suspected when older patients present with chronic low-grade inflammation.

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      참고문헌 (Reference)

      1 Dalle S, "The role of inflammation in age-related sarcopenia" 8 : 1045-, 2017

      2 Xue QL, "The frailty syndrome: definition and natural history" 27 : 1-15, 2011

      3 Blasko I, "TNFalpha plus IFNgamma induce the production of Alzheimer beta-amyloid peptides and decrease the secretion of APPs" 13 : 63-68, 1999

      4 Batsis JA, "Sarcopenia, sarcopenic obesity and inflammation: results from the 1999-2004 National Health and Nutrition Examination Survey" 35 : 1472-1483, 2016

      5 Hida T, "Sarcopenia and physical function are associated with inflam-mation and arteriosclerosis in community-dwelling people: the Yakumo study" 28 : 345-350, 2018

      6 Sastre M, "Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists mod-ulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase" 23 : 9796-9804, 2003

      7 Heneka MT, "Neuroinflammation in Alzheimer’s disease" 14 : 388-405, 2015

      8 Bano G, "Inflammation and sarcopenia: a systematic review and meta-analysis" 96 : 10-15, 2017

      9 Büttner R, "Inflammaging impairs peripheral nerve maintenance and regeneration" 17 : e12833-, 2018

      10 Frasca D, "Inflammaging decreases adaptive and innate immune responses in mice and humans" 17 : 7-19, 2016

      1 Dalle S, "The role of inflammation in age-related sarcopenia" 8 : 1045-, 2017

      2 Xue QL, "The frailty syndrome: definition and natural history" 27 : 1-15, 2011

      3 Blasko I, "TNFalpha plus IFNgamma induce the production of Alzheimer beta-amyloid peptides and decrease the secretion of APPs" 13 : 63-68, 1999

      4 Batsis JA, "Sarcopenia, sarcopenic obesity and inflammation: results from the 1999-2004 National Health and Nutrition Examination Survey" 35 : 1472-1483, 2016

      5 Hida T, "Sarcopenia and physical function are associated with inflam-mation and arteriosclerosis in community-dwelling people: the Yakumo study" 28 : 345-350, 2018

      6 Sastre M, "Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists mod-ulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase" 23 : 9796-9804, 2003

      7 Heneka MT, "Neuroinflammation in Alzheimer’s disease" 14 : 388-405, 2015

      8 Bano G, "Inflammation and sarcopenia: a systematic review and meta-analysis" 96 : 10-15, 2017

      9 Büttner R, "Inflammaging impairs peripheral nerve maintenance and regeneration" 17 : e12833-, 2018

      10 Frasca D, "Inflammaging decreases adaptive and innate immune responses in mice and humans" 17 : 7-19, 2016

      11 Franceschi C, "Inflamm-aging. An evolutionary perspective on immunosenescence" 908 : 244-254, 2000

      12 Hak Chul Jang, "How to Diagnose Sarcopenia in Korean Older Adults?" 대한노인병학회 22 (22): 73-79, 2018

      13 Fried LP, "Frailty in older adults: evidence for a phenotype" 56 : M146-M156, 2001

      14 Wu IC, "Emerging roles of frailty and inflam-maging in risk assessment of age-related chronic diseases in older adults: the intersection between aging biology and personalized medicine" 5 : 1-, 2015

      15 Moo-Young Kim, "Development of a Consensus List of Potentially Inappropriate Medications for Korean Older Adults" 대한노인병학회 22 (22): 121-129, 2018

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      유사연구자 (20) 활용도상위20명

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2022 평가예정 재인증평가 신청대상 (재인증)
      2019-01-01 평가 등재학술지 선정 (계속평가) KCI등재
      2018-12-01 평가 등재후보로 하락 (계속평가) KCI등재후보
      2016-09-02 학술지명변경 한글명 : 노인병 -> Annals of geriatric medicine and research
      외국어명 : Journal of Geriatric Medicine and Research -> Annals of geriatric medicine and research
      KCI등재
      2016-07-12 학술지명변경 외국어명 : Journal of The korean Geriatrics Society -> Journal of Geriatric Medicine and Research KCI등재
      2015-01-01 평가 등재학술지 선정 (계속평가) KCI등재
      2013-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2012-01-01 평가 등재후보학술지 유지 (기타) KCI등재후보
      2011-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2009-01-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.27 0.27 0.29
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.4 0.39 0.678 0.15
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