1 Shulman GI, "Unraveling the cellular mechanism of insulin resistance in humans: new insights from magnetic resonance spectroscopy" 19 : 183-190, 2004
2 Harwood HJ Jr, "Treating the metabolic syndrome: acetyl-CoA carboxylase inhibition" 9 : 267-281, 2005
3 Kim JK, "Tissue-specific overexpression of lipoprotein lipase causes tissue -specific insulin resistance" 98 : 7522-7527, 2001
4 Gavrilova O, "Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice" 105 : 271-278, 2000
5 Choi CS, "Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance" 282 : 22678-22688, 2007
6 Naya FJ, "Stimulation of slow skeletal muscle fiber gene expression by calcineurin in vivo" 275 : 4545-4548, 2000
7 Warram JH, "Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents" 113 : 909-915, 1990
8 Wang H, "Skeletal muscle-specific deletion of lipoprotein lipase enhances insulin signaling in skeletal muscle but causes insulin resistance in liver and other tissues" 58 : 116-124, 2009
9 Petersen KF, "Reversal of nonalcoholic hepatic steatosis, hepatic insulin resistance, and hyperglycemia by moderate weight reduction in patients with type 2 diabetes" 54 : 603-608, 2005
10 Savage DB, "Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2" 116 : 817-824, 2006
1 Shulman GI, "Unraveling the cellular mechanism of insulin resistance in humans: new insights from magnetic resonance spectroscopy" 19 : 183-190, 2004
2 Harwood HJ Jr, "Treating the metabolic syndrome: acetyl-CoA carboxylase inhibition" 9 : 267-281, 2005
3 Kim JK, "Tissue-specific overexpression of lipoprotein lipase causes tissue -specific insulin resistance" 98 : 7522-7527, 2001
4 Gavrilova O, "Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice" 105 : 271-278, 2000
5 Choi CS, "Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance" 282 : 22678-22688, 2007
6 Naya FJ, "Stimulation of slow skeletal muscle fiber gene expression by calcineurin in vivo" 275 : 4545-4548, 2000
7 Warram JH, "Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents" 113 : 909-915, 1990
8 Wang H, "Skeletal muscle-specific deletion of lipoprotein lipase enhances insulin signaling in skeletal muscle but causes insulin resistance in liver and other tissues" 58 : 116-124, 2009
9 Petersen KF, "Reversal of nonalcoholic hepatic steatosis, hepatic insulin resistance, and hyperglycemia by moderate weight reduction in patients with type 2 diabetes" 54 : 603-608, 2005
10 Savage DB, "Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2" 116 : 817-824, 2006
11 Wang YX, "Regulation of muscle fiber type and running endurance by PPARdelta" 2 : e294-, 2004
12 Morino K, "Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents" 115 : 3587-3593, 2005
13 Kim JK, "Prevention of fat-induced insulin resistance by salicylate" 108 : 437-446, 2001
14 Buchanan TA, "Preservation of pancreatic beta-cell function and prevention of type 2 diabetes by pharmacological treatment of insulin resistance in high-risk hispanic women" 51 : 2796-2803, 2002
15 DeFronzo RA, "Pathogenesis of NIDDM. A balanced overview" 15 : 318-368, 1992
16 Choi CS, "Paradoxical effects of increased expression of PGC-1alpha on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism" 105 : 19926-19931, 2008
17 Choi CS, "Overexpression of uncoupling protein 3 in skeletal muscle protects against fat-induced insulin resistance" 117 : 1995-2003, 2007
18 Weisberg SP, "Obesity is associated with macrophage accumulation in adipose tissue" 112 : 1796-1808, 2003
19 Petersen KF, "Mitochondrial dysfunction in the elderly: possible role in insulin resistance" 300 : 1140-1142, 2003
20 Lowell BB, "Mitochondrial dysfunction and type 2 diabetes" 307 : 384-387, 2005
21 Salway JG, "Metabolism at a Glance. 3rd ed" Wiley-Blackwell 2004
22 DeFronzo RA, "Lilly Lecture 1987. The triumvirate: β-cell, muscle, liver. A collusion responsible for NIDDM" 37 : 667-687, 1988
23 Petersen KF, "Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy" 109 : 1345-1350, 2002
24 Krssak M, "Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study" 42 : 113-116, 1999
25 Lillioja S, "Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians" 329 : 1988-1992, 1993
26 Holland WL, "Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance" 5 : 167-179, 2007
27 Grigsby RJ, "Inhibition of ceramide production reverses TNF-induced insulin resistance" 287 : 1121-1124, 2001
28 An J, "Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance" 10 : 268-274, 2004
29 Danforth E Jr, "Failure of adipocyte differentiation causes type II diabetes mellitus?" 26 : 13-, 2000
30 Fink RI, "Evidence that glucose transport is rate-limiting for in vivo glucose uptake" 41 : 897-902, 1992
31 Kim HJ, "Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo" 53 : 1060-1067, 2004
32 Taniguchi CM, "Critical nodes in signalling pathways: insights into insulin action" 7 : 85-96, 2006
33 Choi CS, "Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity" 104 : 16480-16485, 2007
34 Xu H, "Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance" 112 : 1821-1830, 2003
35 Shulman GI, "Cellular mechanisms of insulin resistance" 106 : 171-176, 2000
36 Michikawa Y, "Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication" 286 : 774-779, 1999
37 Hotamisligil GS, "Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance" 259 : 87-91, 1993
38 Summers SA, "A role for sphingolipids in producing the common features of type 2 diabetes, metabolic syndrome X, and Cushing's syndrome" 54 : 591-602, 2005
39 Hirosumi J, "A central role for JNK in obesity and insulin resistance" 420 : 333-336, 2002