위축성 위염과 장상피화생의 조직학적 진단 = Histopathologic Diagnosis of Atrophic Gastritis and Intestinal Metaplasia

다국어 초록 (Multilingual Abstract)

Atrophic gastritis and intestinal metaplasia are well-known to be reliable indicators of gastric cancer risk. They are clinically important in deciding whether to recommend endoscopic surveillance. Herein I review the histopathologic diagnosis of atrophic gastritis and IM. Gastric atrophy is divided into metaplastic atrophy and non-metaplastic atrophy. IM is categorized as complete (type I) and incomplete (type II, III). Systematic interpretation of gastric atrophy and IM using the updated Sydney system or operative link on gastritis assessment is recommended. Furthermore, I suggest using the consensus definition of gastric atrophy and incomplete IM in the gastric biopsy pathology report to support the surveillance of high-risk gastric cancer group.

참고문헌 (Reference)

1 Capelle LG, "The staging of gastritis with the OLGA system by using intestinal metaplasia as an accurate alternative for atrophic gastritis" 71 : 1150-1158, 2010

2 Jass JR, "The mucin profiles of normal gastric mucosa, intestinal metaplasia and its variants and gastric carcinoma" 13 : 931-939, 1981

3 Gutierrez-Gonzalez L, "The clonal origins of dysplasia from intestinal metaplasia in the human stomach" 140 : 1251-1260.e6, 2011

4 Rugge M, "Staging gastritis : an international proposal" 129 : 1807-1808, 2005

5 Kang KP, "Role of intestinal metaplasia subtyping in the risk of gastric cancer in Korea" 24 : 140-148, 2009

6 Correa P, "Pathology of gastric intestinal metaplasia : clinical implications" 105 : 493-498, 2010

7 Offerhaus GJ, "Observer agreement on the grading of gastric atrophy" 34 : 320-325, 1999

8 Sugano K, "Kyoto global consensus report on Helicobacter pylori gastritis" 64 : 1353-1367, 2015

9 Filipe MI, "Intestinal metaplasia types and the risk of gastric cancer : a cohort study in Slovenia" 57 : 324-329, 1994

10 Chen XY, "Interobserver variation in the histopathological scoring of Helicobacter pylori related gastritis" 52 : 612-615, 1999

11 el-Zimaity HM, "Interobserver variation in the histopathological assessment of Helicobacter pylori gastritis" 27 : 35-41, 1996

12 Aydin O, "Interobserver variation in histopathological assessment of Helicobacter pylori gastritis" 9 : 2232-2235, 2003

13 Leja M, "Interobserver variation in assessment of gastric premalignant lesions : higher agreement for intestinal metaplasia than for atrophy" 25 : 694-699, 2013

14 Padmanabhan N, "How to stomach an epigenetic insult : the gastric cancer epigenome" 14 : 467-478, 2017

15 El-Zumanity H, "Histology for pathologist" Lippincott Williams & Williams 2012

16 Rugge M, "Gastritis staging in the endoscopic follow-up for the secondary prevention of gastric cancer : a 5-year prospective study of 1755 patients" 68 : 11-17, 2019

17 Inada K, "Gastric and intestinal mixed and solely intestinal types of intestinal metaplasia in the human stomach" 47 : 831-841, 1997

18 Kim SS, "Factors to improve the interobserver agreement for gastric atrophy and intestinal metaplasia : consensus of definition and criteria" 72 : 838-845, 2018

19 Rokkas T, "Detection of an increased incidence of early gastric cancer in patients with intestinal metaplasia type III who are closely followed up" 32 : 1110-1113, 1991

20 Dixon MF, "Classification and grading of gastritis. The updated Sydney system. International workshop on the histopathology of gastritis, Houston 1994" 20 : 1161-1181, 1996

21 Greenlee RT, "Cancer statistics, 2000" 50 : 7-33, 2000

22 Ministry of Health and Welfare, "Annual report of cancer statistics in Korea in 2016" National Cancer Center 2018

23 Tan D, "Advances in surgical pathology: gastric cancer" Lippincott Williams & Williams 2011

24 Park DY, "Adenomatous and foveolar gastric dysplasia : distinct patterns of mucin expression and background intestinal metaplasia" 32 : 524-533, 2008