膵臟吸蟲症에 대한 Niclofolan (Bilevon-R)의 驅蟲效果 = Anthelmintic Efficacy of Niclofolan (Bilevon-R) against Eurytremiasis

다국어 초록 (Multilingual Abstract)

The domestic animals in Korea, especially Korean native cattle, are suffering from eurytremiasis. For instance, the cattle in Korea show much higher infection rates of Eurytrema spp. than the cattle in any other country.
They vary from 50 to 80% depending on the area surveyed.
It has to be born in mind that eurytremiasis is a herd problem in Korea. But, there is no report that any suitable therapeutic agents for eurytremiasis of the cattle, sheep and goat. This study was investigated in order to examine the anthelmintic efficacy of Niclofolan (Bilevon-R) against eurytremiasis in goats.
Oral administration of Niclofolan (once a day for 2 succeed days, at the rate of 6 mg per Kg of body weight) were completely devoid the fluke eggs in the feces of goats on 3-15 days after treatment. After drug adminstrations, transient side effects are shown such as anorexia, depression, soft feces and accelerated breathing. The possibility that goat eurytremiasis could be treated with only 2 doses of Niclofolan has been proved by this study. Therefore Niclofolan is a very promising drug for treatment against eurytremiasis of the cattle.