산돌배나무(Pyrus ussuriensis)잎 추출물의 항산화활성에 관한 연구 = Study on Anti-oxidant Effect of Extracts from Pyrus ussuriensis Leaves

다국어 초록 (Multilingual Abstract)

The aim of the study was to assess the cosmeceutical activity of Pyrus ussuriensis leaves and it is possible that can be used as a cosmetic ingredient for application of cosmetic industries. P t1sslirensis leaf was extracted with various solvents including water, 70% ethanol and 60% acetone. In the result of DPPH (J, 1diphenyl-2-picryl-hydrazyl) scavenging radical activity, water, ethanol and acetone extract of P. ussuriensis leaf were higher than 70%, 80% and 85`Vo at 50 ppm concentration, respectively. Xanthine oxidase inhibition activity and superoxide dismutase (SOD)-like activity by P ussuriensis extract were higher than 30%. In addition, SOD-like activity of all extracts showed tendency of the significant increase with the increase of concentration. In the anti-inflammatory test, P. ussuriensis leaf extract inhibited generation of nitric oxide (NO) stimulated by LPS in the macrophage cell line (raw :264.7) after 12 to 24 hours. As above results, P t1SSlIriensis has a great potential as a cosmeceutical raw material as well as anti-oxidant and anti-inflammatory ability.

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