만성부비동염에서 전산화단층촬영과 병리조직학적 소견과의 관계：만성염증의 중증도에 대한 지표 = Relationship between CT Scores and Pathologic Findings in Chronic Sinusitis : The Indicators of Severity in Chronic Inflammation

다국어 초록 (Multilingual Abstract)

Background and Objectives：Chronic sinusitis is a comon disease in otolaryngology, but its pathologic mechanism has not been clearly known. Also, the evaluation method for the severity of chronic sinusitis is not established. The aim of this study was to analyze possible factors associated with the correlation betwen the radiological and pathological severity of chronic sinusitis. In addition, we assesed the profiles of inflammatory cells in the sinus mucosa and peripheral blood eosinophils in relation to the overall pathologic grades and OMU CT findings. Subjects and Method：Fifty specimens of pathologic sinus mucosa, obtained during endoscopic sinus surgery were stained with hematoxylin and eosin. Total inflammatory cels, plasma cells, neutrophils, lymphocytes and eosinophils were quantified. The preoperative OMU CT scans were scored by the staging system of Lund-Mackay. Also, the preoperative percentage of eosinophils in peripheral white blood cells were obtained with the complete blood count with differentiation. Results：The count of total inflamatory cells, lymphocytes and eosinophils infiltrated in the diseased sinus sed by Lund-Mackay system corelated significantly with the severity of the pathologic grades. Conclusion：The important in-dicators of the severity of the chronic inflamation in chronic sinusitis were OMU CT scores, overal pathologic grades, and total inflamatory cells, lymphocytes and eosinophils infiltrated in sinus mucosa.

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