化痰·止咳平喘藥이 Acetylcholine에 의한 흰쥐의 氣管支平滑筋의 收縮에 미치는 影響 = The Effects of Whoa Dam-Ji Hae Pyung Chun Yak on Contracted Tracheal Smooth Muscle with Acetylcholine in Rat

다국어 초록 (Multilingual Abstract)

This study was performed to analyze the effects of WhoaDam-jiHae PyeougChunYak on contracted tracheal smooth muscle in rat.
Transverse strips were used for the experiment using organ bath.
The test strip was perfused with modified Krebs-Ringer Bicarbonate solution which was aerated with 95% O₂- 5% CO₂ mixed gas and kept at 37℃.
WhoaDam-jiHae PyeougChunYak extract and acetylcholine infused tracheal strip that was contracted with acetylcholine.
The results were as follows ;
1. The contractile force of tracheal strip by acetylcholine was significantly increased by Pinelliae Rhizoma, Arisaematis Rhizoma, Sinapis Semen, Typhonii Rhizoma, Peucedani Radix, Eriobotryae Folium, Platicodi Radix, Bambusae Caulis Taeniam, Benincasae Semen, Armeniacae Amarum Semen, Asteris Radix, Perillae Fructus, Mori cortex and Lepidii Semen.
2. Arisaematis Rhizoma(1㎕/㎖, 3㎕/㎖, 10㎕/㎖) and Asteris Radix(1㎕/㎖, 3㎕/㎖) slightly relaxed the contracted tracheal strip by acetylcholine.
3. Farfarae Flos significantly relaxed the contracted tracheal strip by acetylcholine.
4. The contractile force of tracheal srtip by acetylcholine was significantly increased by Stemonae Radix at 30㎕/㎖, on the other hand Stemonae Radix 100㎕/㎖ significantly relaxed the contracted tracheal strip by acetylcholine.