In order to clarify the influence of chronic renal failure and hemodialysis on plasma prolactin concentration, plasma prolactin concentration was measured in 7 patients with chronic renal failure receiving conservative treatment, 12 uremic patients on...
In order to clarify the influence of chronic renal failure and hemodialysis on plasma prolactin concentration, plasma prolactin concentration was measured in 7 patients with chronic renal failure receiving conservative treatment, 12 uremic patients on intermittent hemodialysis and 10 subjects with normal renal function. The results were as follows: 1) There was marked elevation of plasma prolactin concentration in the patients with chronic renal failure as compared to the patients with normal renal function. 2) There was a positive correlation between plasma prolactin concentration and plasma creatinine, but there was no significant correlation between plasma prolactin concentration and BUN. 3) In 12 subjects undergoing hemodialysis, there was no significant change of plasma prolactin concentration between before and after hemodialysis.