The purpose of the study is to determine the effects of Zn in lead poisoning rats by way of examining interaction mechanism of Pb and Zn.
The fifty-five rats were Pb divided into four groups such as Zn group, group , Pb and Zn group , and contro1 gro...
The purpose of the study is to determine the effects of Zn in lead poisoning rats by way of examining interaction mechanism of Pb and Zn.
The fifty-five rats were Pb divided into four groups such as Zn group, group , Pb and Zn group , and contro1 group. The rats of Zn group and of Zn and Pb group were subdividedinto four groups by dose of Zn respectively ; 250 mglt , 500 mglt , 1,000 mg It and 2,OOOmg/l.
The rats having been fed the above mentioned chemica1s, were weighed everγ five days for fifty-five days, and the subjects were slaughtered for measuring ò - ALAD activities in blood and the accumulation amount of the chemicals in livers and kidneys.
The resu1ts of the study are summarized as following ;
L As for body weight gains , those of the ∞ntrol group rats were the highest , and thoseof Pb group the lowest.
2. ò - ALAD activities of Pb group showed the tendency of decrease in com parison with those of control group. 1n Zn group , the subgroups of 250 mg/l and 500 mg/ 1 showedhigher activities than control group , whereas the subgroups of 1,000 π‘ r; /l and 2,000 mg/l showed lower.
3. Hb value of Pb group was lower than that of control group. 1n Zn group , Hb V8- lue of the groups of 250mg/1 and 500mg/I was a little higher than that of control group , while that of the groups of 1,000 mg/l and 2,000 mg/l was lower.