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      만성 뇌졸중 후 편마비 환자에서 2주간 경두개 전기 자극 후 상지 운동기능 향상 = Improvement of Chronic Post-Stroke Hemiparetic Upper Limb Function after 2 Week Trascranial Direct Current Stimulation

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      https://www.riss.kr/link?id=A101632252

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      다국어 초록 (Multilingual Abstract)

      Objective: To investigate whether transcranial direct current stimulation (tDCS) could improve the motor function of hemiparetic upper limb in chronic stroke patients through randomized double-blinded, sham-controlled study. Method: Twenty chronic po...

      Objective: To investigate whether transcranial direct current stimulation (tDCS) could improve the motor function of hemiparetic upper limb in chronic stroke patients through randomized double-blinded, sham-controlled study.
      Method: Twenty chronic post-stroke hemiparetic patients participated in this study. They were randomly assigned into either tDCS or sham group. Anodal tDCS was delivered on lesional primary motor cortex for 20 minutes in tDCS group and 30 seconds in sham group. Just after stimulation, both groups performed the shaping exercise for 30 minutes. Total 10 stimulation sessions (5 session/week for 2 weeks) were administered. Fugl-Meyer motor assessment, box and block test, grasp strength and FIM were assessed before stimulation, after 1 week of stimulation, after 2 weeks of stimulation, and 2 weeks after stimulation.
      Results: The upper extremity score of Fugl-Meyer motor assessment and box and block test improved significantly in tDCS group compared to sham group (p<0.05). Their improvement lasted significantly for 2 week after stimulation. However, FIM, lower extremity score of Fugl-Meyer motor assessment and grasp power did not improved significantly in tDCS group compared to sham group.
      Conclusion: tDCS can improve the motor function of hemiparetic upper limb in chronic post-stroke patients, and the effects lasted after stimulation. tDCS may be used as an additional tool for stroke rehabilitation.

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      다국어 초록 (Multilingual Abstract)

      Objective: To investigate whether transcranial direct current stimulation (tDCS) could improve the motor function of hemiparetic upper limb in chronic stroke patients through randomized double-blinded, sham-controlled study. Method: Twenty chronic pos...

      Objective: To investigate whether transcranial direct current stimulation (tDCS) could improve the motor function of hemiparetic upper limb in chronic stroke patients through randomized double-blinded, sham-controlled study.
      Method: Twenty chronic post-stroke hemiparetic patients participated in this study. They were randomly assigned into either tDCS or sham group. Anodal tDCS was delivered on lesional primary motor cortex for 20 minutes in tDCS group and 30 seconds in sham group. Just after stimulation, both groups performed the shaping exercise for 30 minutes. Total 10 stimulation sessions (5 session/week for 2 weeks) were administered. Fugl-Meyer motor assessment, box and block test, grasp strength and FIM were assessed before stimulation, after 1 week of stimulation, after 2 weeks of stimulation, and 2 weeks after stimulation.
      Results: The upper extremity score of Fugl-Meyer motor assessment and box and block test improved significantly in tDCS group compared to sham group (p<0.05). Their improvement lasted significantly for 2 week after stimulation. However, FIM, lower extremity score of Fugl-Meyer motor assessment and grasp power did not improved significantly in tDCS group compared to sham group.
      Conclusion: tDCS can improve the motor function of hemiparetic upper limb in chronic post-stroke patients, and the effects lasted after stimulation. tDCS may be used as an additional tool for stroke rehabilitation.

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      참고문헌 (Reference)

      1 Fregni F, "Transcranial direct current stimulation of the unaffected hemisphere in stroke patients" 16 : 1551-1555, 2005

      2 Liepert J, "Training- induced changes of motor cortex representations in stroke patients" 101 : 321-326, 2000

      3 Fugl-Meyer AR, "The post-stroke hemiplegic patient. 1. a method for evaluation of physical performance" 7 : 13-31, 1975

      4 Iyer MB, "Safety and cognitive effect of frontal DC brain polarization in healthy individuals" 64 : 872-875, 2005

      5 Muellbacher W, "Role of the human motor cortex in rapid motor learning" 136 : 431-438, 2001

      6 Boggio PS, "Repeated sessions of noninvasive brain DC stimulation is associated with motor function improvement in stroke patients" 25 : 123-129, 2007

      7 Platz T, "Reliability and validity of arm function assessment with standardized guidelines for the Fugl-Meyer test, action research arm test and box and block test: a multicentre study" 19 : 404-411, 2005

      8 Nakayama H, "Recovery of upper extremity function in stroke patients: the Copenhagen Stroke Study" 75 : 394-398, 1994

      9 Classen J, "Rapid plasticity of human cortical movement representation induced by practice" 79 : 1117-1123, 1998

      10 Nitsche MA, "Modulating parameters of excitability during and after transcranial direct current stimulation of the human motor cortex" 568 : 291-303, 2005

      1 Fregni F, "Transcranial direct current stimulation of the unaffected hemisphere in stroke patients" 16 : 1551-1555, 2005

      2 Liepert J, "Training- induced changes of motor cortex representations in stroke patients" 101 : 321-326, 2000

      3 Fugl-Meyer AR, "The post-stroke hemiplegic patient. 1. a method for evaluation of physical performance" 7 : 13-31, 1975

      4 Iyer MB, "Safety and cognitive effect of frontal DC brain polarization in healthy individuals" 64 : 872-875, 2005

      5 Muellbacher W, "Role of the human motor cortex in rapid motor learning" 136 : 431-438, 2001

      6 Boggio PS, "Repeated sessions of noninvasive brain DC stimulation is associated with motor function improvement in stroke patients" 25 : 123-129, 2007

      7 Platz T, "Reliability and validity of arm function assessment with standardized guidelines for the Fugl-Meyer test, action research arm test and box and block test: a multicentre study" 19 : 404-411, 2005

      8 Nakayama H, "Recovery of upper extremity function in stroke patients: the Copenhagen Stroke Study" 75 : 394-398, 1994

      9 Classen J, "Rapid plasticity of human cortical movement representation induced by practice" 79 : 1117-1123, 1998

      10 Nitsche MA, "Modulating parameters of excitability during and after transcranial direct current stimulation of the human motor cortex" 568 : 291-303, 2005

      11 Duncan PW, "Measurement of motor recovery after stroke. Outcome assessment and sample size requirements" 23 : 1084-1089, 1992

      12 Walsh V, "Manipulating brains" 17 : 131-134, 2006

      13 Nitsche MA, "Level of action of cathodal DC polarisation induced inhibition of the human motor cortex" 114 : 600-604, 2003

      14 Hamilton BB, "Interrater reliability of the 7-level functional independence measure (FIM)" 26 : 115-119, 1994

      15 Floel A, "Influence of somatosensory input on motor function in patients with chronic stroke" 56 : 206-212, 2004

      16 Liepert J, "Improvement of dexterity by single session low-frequency repetitive transcranial magnetic stimulation over the contralesional motor cortex in acute stroke: a double-blind placebo-controlled crossover trial" 25 : 461-465, 2007

      17 Lang N, "How does transcranial DC stimulation of the primary motor cortex alter regional neuronal activity in the human brain?" 22 : 495-504, 2005

      18 Nitsche MA, "GABAergic modulation of DC stimulation-induced motor cortex excitability shifts in humans" 19 : 2720-2726, 2004

      19 Nitsche MA, "Facilitation of implicit motor learning by weak transcranial direct current stimulation of the primary motor cortex in the human" 15 : 619-626, 2003

      20 Nitsche MA, "Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation" 527 : 633-639, 2000

      21 Boggio PS, "Enhancement of non-dominant hand motor function by anodal transcranial direct current stimulation" 404 : 232-236, 2006

      22 Sawaki L, "Effects of somatosensory stimulation on use-dependent plasticity in chronic stroke" 37 : 246-247, 2006

      23 Hummel F, "Effects of non-invasive cortical stimulation on skilled motor function in chronic stroke" 128 : 490-499, 2005

      24 Hummel FC, "Effects of brain polarization on reaction times and pinch force in chronic stroke" 7 : 73-, 2006

      25 Scheidtmann K, "Effect of levodopa in combination with physiotherapy on functional motor recovery after stroke: a prospective, randomised, double- blind study" 358 : 787-790, 2001

      26 Fraser C, "Driving plasticity in human adult motor cortex is associated with improved motor function after brain injury" 34 : 831-840, 2002

      27 Uswatte G, "Contribution of the shaping and restraint components of constraint-induced movement therapy to treatment outcome" 21 : 147-156, 2006

      28 Taub E, "A placebo-controlled trial of constraint-induced movement therapy for upper extremity after stroke" 37 : 1045-1049, 2006

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      학술지 이력

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      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.19 0.19 0.17
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.19 0.19 0.397 0.01
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