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      KCI등재 SCIE SCOPUS

      Medicinal Herbs Effective Against Atherosclerosis: Classification According to Mechanism of Action

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      https://www.riss.kr/link?id=A106172265

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      다국어 초록 (Multilingual Abstract)

      Atherosclerosis is a widespread and chronic progressive arterial disease that has been regarded as one of the major causes of death worldwide. It is caused by the deposition of cholesterol, fats, and other substances in the tunica intima which leads t...

      Atherosclerosis is a widespread and chronic progressive arterial disease that has been regarded as one of the major causes of death worldwide. It is caused by the deposition of cholesterol, fats, and other substances in the tunica intima which leads to narrowing of the blood vessels, loss of elasticity, and arterial wall thickening, thus causing difficulty in blood flow. Natural products have been used as one of the most important strategies for the treatment and prevention of cardiovascular diseases for a long time. In recent decades, as interests in natural products including medicinal herbs have increased, many studies regarding natural compounds that are effective against atherosclerosis have been conducted. The purpose of this review is to provide a brief overview of the natural compounds that have been used for the treatment and prevention of atherosclerosis, and their mechanisms of action based on recent research.

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      참고문헌 (Reference)

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      8 Jia LQ, "Tanshinone IIA reduces apoptosis induced by hydrogen peroxide in the human endothelium-derived EA.hy926 cells" 143 : 100-108, 2012

      9 Zhu H, "Tanshinone IIA protects endothelial cells from H2O2-induced injuries via PXR activation, Biomol" 25 : 599-608, 2017

      10 Zhang J, "Systems pharmacology dissection of the anti-inflammatory mechanism for the medicinal herb Folium eriobotryae" 16 : 2913-2941, 2015

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      2 Fardoun M, "Ziziphus nummulariainhibits inflammation-induced atherogenic phenotype of human aortic smooth muscle cells" 2017 : 4134093-, 2017

      3 Wang F, "The sonodynamic effect of curcumin on THP-1 cell-derived macrophages" 2013 : 737264-, 2013

      4 박선행, "The protective effect of Prunella vulgaris ethanol extract against vascular inflammation in TNF-α-stimulated human aortic smooth muscle cells" 생화학분자생물학회 46 (46): 352-357, 2013

      5 Insull W., Jr, "The Pathology of Atherosclerosis: Plaque Development and Plaque Responses to Medical Treatment" Elsevier BV 122 (122): S3-S14, 2009

      6 Park SH, "The Korean herbal medicine, Do In Seung Gi-Tang, attenuates atherosclerosis via AMPK in high-fat diet-induced ApoE(−/−)mice" 16 : 352-, 2016

      7 Li YI, "Tanshinone IIA reduces macrophage death induced by hydrogen peroxide by upregulating glutathione peroxidase" 83 : 557-562, 2008

      8 Jia LQ, "Tanshinone IIA reduces apoptosis induced by hydrogen peroxide in the human endothelium-derived EA.hy926 cells" 143 : 100-108, 2012

      9 Zhu H, "Tanshinone IIA protects endothelial cells from H2O2-induced injuries via PXR activation, Biomol" 25 : 599-608, 2017

      10 Zhang J, "Systems pharmacology dissection of the anti-inflammatory mechanism for the medicinal herb Folium eriobotryae" 16 : 2913-2941, 2015

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      16 Lin SJ, "Salvianolic acid B attenuates MMP-2 and MMP-9 expression in vivo in apolipoprotein-E-deficient mouse aorta and in vitro in LPS-treated human aortic smooth muscle cells" 100 : 372-384, 2007

      17 Park SH, "Purple perilla extracts with α-asarone enhance cholesterol efflux from oxidized LDL-exposed macrophages" 35 : 957-965, 2015

      18 Okamura S, "Pueraria mirifica phytoestrogens improve dyslipidemia in postmenopausal women probably by activating estrogen receptor subtypes" 216 : 341-351, 2008

      19 Moon CY, "Protocatechuic aldehyde inhibits migration and proliferation of vascular smooth muscle cells and intravascular thrombosis" 423 : 116-121, 2012

      20 Tong YF, "Protocatechuic aldehyde inhibits TNF-α-induced fibronectin expression in human umbilical vein endothelial cells via a c-Jun N-terminal kinase dependent pathway" 11 : 277-282, 2015

      21 Yao W, "Proteomic analysis for anti-atherosclerotic effect of tetrahydroxystilbene glucoside in rats" 67 : 140-145, 2013

      22 Li JK, "Protective effects of farrerol against hydrogen-peroxide-induced apoptosis in human endothelium-derived EA.hy926 cells" 91 : 733-740, 2013

      23 Chan K, "Protective effects of Danshensu from the aqueous extract of Salvia miltiorrhiza(Danshen)against homocysteine-induced endothelial dysfunction" 75 : 3157-3171, 2004

      24 Manar A Nader, "Protective Effects of Propolis and Thymoquinone on Development of Atherosclerosis in Cholesterol-Fed Rabbits" 대한약학회 33 (33): 637-643, 2010

      25 Wang HT, "Patchouli alcohol attenuates experimental atherosclerosis via inhibiting macrophage infiltration and its inflammatory responses" 83 : 930-935, 2016

      26 Wan JB, "Panax notoginseng reduces atherosclerotic lesions in ApoE-deficient mice and inhibits TNF-alpha-induced endothelial adhesion molecule expression and monocyte adhesion" 57 : 6692-6697, 2009

      27 Nizamutdinova IT, "Paeonol suppresses intercellular adhesion molecule-1 expression in tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells by blocking p38, ERK and nuclear factor-kappaB signaling pathways" 7 : 343-350, 2007

      28 Kattoor AJ, "Oxidative stress in atherosclerosis" 19 : 42-, 2017

      29 Liu Y, "Nuclear transport modulation reduces hypercholesterolemia, atherosclerosis, and fatty liver" 2 : e000093-, 2013

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      31 Campos J, "Lemon grass (Cymbopogon citratus (D.C) Stapf) polyphenols protect human umbilical vein endothelial cell (HUVECs) from oxidative damage induced by high glucose, hydrogen peroxide and oxidised low-density lipoprotein" 151 : 175-181, 2014

      32 Luo Y, "Isorhamnetin attenuates atherosclerosis by inhibiting macrophage apoptosis via PI3K/AKT activation and HO-1 induction" 10 : e0120259-, 2015

      33 François Roubille, "Is hypertriglyceridemia atherogenic?" Elsevier BV 47 (47): 757-763, 2018

      34 Bo Yu, "Inhibition of PAI-1 Activity by Toddalolactone as a Mechanism for Promoting Blood Circulation and Removing Stasis by Chinese Herb Zanthoxylum nitidum var. tomentosum" Frontiers Media SA 8 : 489-, 2017

      35 Napagoda M, "Inhibition of 5-lipoxygenase as anti-inflammatory mode of action of Plectranthus zeylanicus Benth and chemical characterization of ingredients by a mass spectrometric approach" 151 : 800-809, 2014

      36 Tuncer MA, "Influence of Tribulus terrestris extract on lipid profile and endothelial structure in developing atherosclerotic lesions in the aorta of rabbits on a high-cholesterol diet" 111 : 488-500, 2009

      37 Lee LS, "Hypolipidemic and antioxidant properties of phenolic compound-rich extracts from white ginseng(Panax ginseng)in cholesterol-fed rabbits" 18 : 12548-12560, 2013

      38 Yang JX, "Hypolipidemic activity and antiatherosclerotic effect of polysaccharide of Polygonatum sibiricum in rabbit model and related cellular mechanisms" 2015 : 391065-, 2015

      39 Amrani S, "Hypolipidaemic activity of aqueous Ocimum basilicum extract in acute hyperlipidaemia induced by triton WR-1339 in rats and its antioxidant property" 20 : 1040-1045, 2006

      40 Yanping Zou, "Hypocholesterolemic effects of a flavonoid-rich extract of Hypericumperforatum L. in rats fed a cholesterol-rich diet" American Chemical Society (ACS) 53 (53): 2462-2466, 2005

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      42 Zhu X, "Honokiol suppresses TNF-α-induced migration and matrix metalloproteinase expression by blocking NF-κB activation via the ERK signaling pathway in rat aortic smooth muscle cells" 116 : 588-595, 2014

      43 Ling Qiu, "Honokiol ameliorates endothelial dysfunction through suppression of PTX3 expression, a key mediator of IKK/IκB/NF-κB, in atherosclerotic cell model" 생화학분자생물학회 47 : 1-8, 2015

      44 Chen CC, "Hibiscus sabdariffa extract inhibits the development of atherosclerosis in cholesterol-fed rabbits" 51 : 5472-5477, 2003

      45 Chen SC, "Herbal remedy magnolol suppresses IL-6-induced STAT3 activation and gene expression in endothelial cells" 148 : 226-232, 2006

      46 Lee SJ, "Gleditsia sinensis thorn extract inhibits proliferation and TNF-α-induced MMP-9 expression in vascular smooth muscle cells" 40 : 373-386, 2012

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      48 Ho HH, "Extract from the leaf of nucifera reduced the development of atherosclerosis via inhibition of vascular smooth muscle cell proliferation and migration" 48 : 159-168, 2010

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      55 Zhao W, "Danshenol A inhibits TNF-α-induced expression of intercellular adhesion molecule-1(ICAM-1)mediated by NOX4 in endothelial cells" 7 : 12953-, 2017

      56 Choi DH, "Cynanchum wilfordii ameliorates hypertension and endothelial dysfunction in rats fed with high fat/cholesterol diets" 34 : 4-11, 2012

      57 Liu Z, "Cryptotanshinone, an orally bioactive herbal compound from Danshen, attenuates atherosclerosis in apolipoprotein E-deficient mice : role of lectin-like oxidized LDL receptor-1(LOX-1)" 172 : 5661-5675, 2015

      58 Ang KP, "Cryptotanshinone attenuates in vitro oxLDL-induced pre-lesional atherosclerotic events" 77 : 1782-1787, 2011

      59 Kim TJ, "Corynoxeine isolated from the hook of Uncaria rhynchophylla inhibits rat aortic vascular smooth muscle cell proliferation through the blocking of extracellular signal regulated kinase 1/2 phosphorylation" 31 : 2073-2078, 2008

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      65 Chen Y, "Atractylodes lactone compounds inhibit platelet activation" 28 : 194-202, 2017

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      68 Vaidya H, "Antihyperlipidaemic activity of swertiamarin, a secoiridoid glyco-side in poloxamer-407-induced hyperlipidaemic rats" 63 : 437-442, 2009

      69 Duan W, "Antiatherogenic effects of Phyllanthus Emblica associated with corilagin and its analogue" 125 : 587-591, 2005

      70 Lee YJ, "Anti-inflammatory effect of Buddleja officinalis on vascular inflammation in human umbilical vein endothelial cells" 38 : 585-598, 2010

      71 Subramaniam S, "Anti-atherogenic activity of ethanolic fraction of Terminalia arjunabark on hypercholesterolemic rabbits" 2011 : 487916-, 2011

      72 Fu J, "1, 6-Di-O-caffeoyl-β-D-glucopyranoside, a natural compound from Callicarpanudiflora Hook impairs P2Y12 and thromboxane A2 receptor-mediated amplification of platelet activation and aggregation" 36 : 273-282, 2017

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