Nonylphenol에 장기간 노출된 붕어, Carassius auratus 기관계의 조직병리학적 변화 = Histopathological changes in the organs of the crucian carp, Carassius auratus (Teleostei: Cyprinidae) long-term exposed to nonylphenol

다국어 초록 (Multilingual Abstract)

Toxicity of nonylphenol one of EDCs was studied with focus on crucian carp, Carassius
auratus. Fishes were cultured under the control and the nonylphenol exposure conditions
for 32 weeks. Experimental group were composed of total of 4 groups that 1 control condition
and 3 nonylphenol exposure conditions (18.28, 36.76 and 82.70 ㎍ NP L-1). The skin exposed
to nonlyphenol showed degeneration and atrophy of mucous cells, atrophy and necrosis
of epidermal layer and hypertrophy of club cells. In the case of gill, it was showed hyperplasia
of the filament epithelia, appearance of melano macrophage center and lifting of the
lamella epithelial layer. Moreover, in 82.70 ㎍ NP L-1 group, gills showed necrosis of the
filament and lamella. Liver in fish exposed to nonylphenol were characterized by cloudy
cytoplasm, atrophy of nucleus and necrosis of hepatocytes. The kidney of fish exposed to
nonylphenol was observed PAS positive materials in the lumen of the several renal tubule,
appearance of eosinophilic granular cells and necrosis of glomerulus and renal tubule.
Results of this study suggest that nonlyphenol induce severe histopathological changes in
the organs of Carassius auratus.