국내 Epstein-Barr 바이러스 일차감염의 임상적 특성 = Clinical Characteristics of Primary Epstein-Barr Virus Infections in Korea

다국어 초록 (Multilingual Abstract)

In this study, the clinical features of 264 patients of primary Epstein-Barr virus (EBV) infection between the years of 2002-2006 were evaluated retrospectively. The median age of the patients was 6 years old (0-69), and the hospitalization rate was 78.0%. Fever (83.3%) and sore throat (50.4%) were the most common symptoms. Cervical lymphadenopathy (71.2%), tonsillitis (51.1%), splenomegaly (26.1 %), hepatomegaly (25.8%), rash (10.2%) and jaundice (1.5%) were observed. Cervical lymphadenopathy was less frequent in older age groups. The annual number of primary EBV infections according to the age group during the study period did not change significantly in this study.

참고문헌 (Reference)

1 Kang CI, "Seroprevalence of Epstein-Barr virus infection in young men of south Korea" 39 : 93-94, 2007

2 Oh SH, "Prevalence of Epstein- Barr virus antibody in Korean children" 804-11, 1994

3 Kim HS, "Positivity of Epstein-Barr antibodies in 177 pediatric patients" 71-6, 1990

4 Moon WY, "Infectious mononucleosis in children" 822-31, 1994

5 Tattevin P, "Increasing incidence of severe Epstein-Barr virus- related infectious mononucleosis: surveillance study" 44 : 1873-1874, 2006

6 Gartner BC, "Evaluation of four commercially available Epstein-Barr virus enzyme immunoassays with an immunofluorescence assay as the reference method" 10 : 78-82, 2003

7 Weber B, "Evaluation of 11 enzyme immunoassays for the detection of immunoglobulin M antibodies to Epstein-Barr virus" 57 : 87-93, 1996

8 Johannsen EC, "Epstein-Barr virus (infectious mononucleosis)" Philadelphia, Elsevier Inc. 1801-1820, 2005

9 Chung JL, "Clinical usefulness of EBV- specific antibody panel test and PCR genotyping in the diagnosis of Epstein-Barr virus infection" 20 : 320-329, 2000

10 Borer A, "Clinical features and costs of care for hospitalized adults with primary Epstein-Barr virus infection" 107 : 144-148, 1999