Rat에 있어서 사료내 아연의 첨가가 조직내 카드뮴의 농도 및 혈액상에 미치는 영향 = The Effect of Supplemental Zinc on the Tissue Cadimium Concentration and Hematological Picture in Rat

다국어 초록 (Multilingual Abstract)

Present experiment was undrtaken in order to clarify the effect of supplemental zinc on the absorption of cadmium in diet and hematological picture.
The rats were fed with diet containing 10㎍/g of cadmium(Control rats) and the other 10 with the same diet which were added with 2,000㎍/g of zinc(Experimental rats). One half of the rats were sacrified on 30th day and the remainder on 60th day. Kidney, liver, muscle, and hair samples were collected, ashed and analyzed for the cadmium and zinc contents using an atomic absorption spectrophotometer.
In addition, blood samples collected at necropsy were examined for erythrocyte count, complete leukocyte count and packed cell volume.
The result obtained are summrized as follows:
The mean cadmium contents of control group were measured as 0.91㎍/g in liver, 1.23㎍/g in kidney, 0.35㎍/g in muscle and 2.1㎍/g in hair. The mean cadmium contents of experimental group were measured as 0.86㎍/g in liver, 1.49㎍/g in kidney, 0.11㎍/g in muscle and 0.16㎍/g in hair. These values showed no significant difference statistically between the two groups.
The mean zinc contents of control group were measured as 11.39㎍/g in liver, 26.82㎍/g in kidney, 13.14㎍/g in muscle and 60.27㎍/g in hair.
The mean zinc contents of experimental group were measured as 12.75㎍/g in liver, 22.06㎍/g in kidney, 10.17㎍/g in muscle and 70.92㎍/g in hair. No significant difference was recorgnized between the two groups.
The mean hematological pictures of control group were measured as 764×10 exp (4)/cmm in erythrocyte count, 13,830cmm in leukocyte count, 40% in packed cell volume, 12% in neutrophill count, 88% in lymphocyte count and 1% in monocyte count. The mean hematological pictures of experimental group were measured as 686×10 exp (4)/cmm in erythrocyte count, 10,905cmm in leukocyte count, 40% in packed cell volume, 17% in neutrophil count, 83% in lymphocyte count, and 1% in monocyte count. A significant difference(p<0.1) was observable only in the erythrocyte counts of the two groups.

목차 (Table of Contents)

• Ⅰ. 서론
• Ⅱ. 재료 및 방법
• Ⅲ. 결과
• Ⅳ. 고찰
• Ⅴ. 요약