A case of erythematotelangiectatic rosacea successfully treated with carvedilol = A case of erythematotelangiectatic rosacea successfully treated with carvedilol

다국어 초록 (Multilingual Abstract)

According to the National Society of Rosacea, rosacea is classified as erythematotelangiectatic rosacea (ETR), papulopustular rosacea, phymatous rosacea and ocular rosacea. The ETR subtype is typified by frequent episodes of facial flushing, telangiectasias, and persistent centrofacial erythema. Severe flushing can cause significant physical discomfort and emotional stress to the patients, and currently no satisfactory treatments are available. Nonselective ß-blockers decrease sympathetic activity and also have been reported to suppress flushing. The mechanism of ß-blockers in treating ETR may be by way of blocking the ß2-adrenergic receptor on the smooth muscle of cutaneous arterial blood vessels, resulting in vasoconstriction. Especially carvedilol, a nonselective ß-adrenergic blocking agent, demonstrated more potent antioxidant properties compared with other ß blockers and may offer an added advantage over the traditional ß blockers. A 35-year-old man presented with facial flushing with persistent erythema, and telangiectasia accompanied by burning and itchy sensation that provoked by various stimuli, including seasonal variation and stress. The patient was diagnosed with ETR and treated with carvedilol 6.25mg daily. The symptoms of ETR were improved with minimal facial erythema and flushing without a hot or burning sensation. Herein we report a case of ETR successfully treated with carvedilol.