A case of lobulated intradermal nevus in young woman = A case of lobulated intradermal nevus in young woman

다국어 초록 (Multilingual Abstract)

Lobulated intradermal nevus is first reported by Cho et al. in 1998 with an unusual growth pattern and appearance in three patients, differed from previously described clinical types. It is a rare variant of melanocytic nevus characterized by the distinct clinicohistopathological findings. In all reported studies about lobulated intradermal nevus cases, the nevus clinically shows lobulation and manifests as corymbiform, raspberry-like or verrucous plaque. And most patients reported was 20 to 30 years old female. The nevus histopathologically presents as fat cell infiltration, neuroid differentiation of nevus cells and dermal fibrosis. This is regarded as a sign of regression of melanocytic nevus. A 26-year-old woman presented with a tumor on vertex. It was 10 years ago and had slowly been protruding from the skin surface. The lesion was a 1.2x1.0cm sized brown to black raspberry-shaped tumor. A shaving biopsy was done and histologic findings revealed the architecture of intradermal nevus with numerous isolated spaces filled with nevus cells. In contrast with other studies, there were no histopahological findings such as fat cell infiltration, neuroid diffentiation of nevus cells and dermal fibrosis. But in other studies, the onset was almost congenital or 30 years ago. In our case, the onset was 10 years and we think that the time was not enough to the regression of nevus cells.