Height-Based Formula Predicting Renal Length in Korean Children derived from Technesium-99m Dimercaptosuccinic Acid Scan

다국어 초록 (Multilingual Abstract)

Purpose: The aim of this study was to establish a simple formula to predict renal length in children using a Technesium-99m dimercaptosuccinic acid (DMSA) scan data, and to compare it with the formula derived from ultrasonography, which is widely accepted.
Methods: Children who underwent a DMSA scan and ultrasonography were reviewed retrospectively, and those who had anatomical urinary tract abnormalities or urinary tract infections were excluded.
Results: A total of 230 children (84 males and 146 females; age, 1 month to 16 years; mean age, 16.8 ± 27.4 months). Mean renal length measured by DMSA scan was longer than that by ultrasonography (6.38 ± 1.16 vs. 6.02 ± 1.14 cm; P < 0.001).
Renal length was correlated with age, weight, height, and body surface area on the DMSA scan and ultrasonography, and showed the strongest positive correlation with height. The following formulae were established to predict renal length: mean renal length (cm) = 5.433 × height (m) + 2.330 (R2, 0.833) using the DMSA scan data, and mean renal length (cm) = 5.367 × height (m) + 2.027 (R2, 0.853) using ultrasonography data.
Conclusion: We propose a simple height-based formula to predict renal length in children using a DMSA scan data, and validate it by comparing with ultrasonography formula.

참고문헌 (Reference)

1 Chen JJ, "The renal length nomogram : Mul t ivar iable approach" 168 : 2149-2152, 2002

2 Rossleigh MA, "Technetium-99m dimercaptosuccinic acid scintigraphy studies of renal cortical scarring and renal length" 39 : 1280-1285, 1998

3 Han BK, "Sonographic measurements and appearance of normal kidneys in children" 145 : 611-616, 1985

4 O’Neill WC, "Sonographic evaluation of renal failure" 35 : 1021-1038, 2000

5 Zerin JM, "Sonographic assessment of renal length in children : A reappraisal" 24 : 101-106, 1994

6 Akhavan A, "Simple, age-based formula for predicting renal length in children" 78 : 405-410, 2011

7 Lin E, "Reproducibility of renal length measurements with 99mTc-DMSA SPECT" 41 : 1632-1635, 2000

8 Lobo Sotomayor G, "Renal size in children with normal renal 99mTc-DMSA scan : Building a nomogram with scintigraphic length" 23 : 102-105, 2004

9 Sisayan RM, "Nomograms of renal length in children obtained from DMSA scintigraphy" 18 : 970-973, 1993

10 김준휘, "Length and Volume of Morphologically Normal Kidneys in Korean Children: Ultrasound Measurement and Estimation Using Body Size" 대한영상의학회 14 (14): 677-682, 2013

11 이민정, "Kidney size estimation in Korean children with Technesium-99m dimercaptosuccinic acid scintigraphy" 대한소아과학회 57 (57): 41-45, 2014

12 Schmidt IM, "Kidney growth in 717 healthy children aged 0-18 months : A longitudinal cohort study" 19 : 992-1003, 2004

13 Emamian SA, "Kidney dimensions at sonography: Correlation with age, sex, and habitus in 665adult volunteers" 160 : 83-86, 1993

14 Schlesinger AE, "Interobserver and intraobserver variations in sonographic renal length measurements in children" 156 : 1029-1032, 1991

15 Boo Won Kim, "Evaluation of kidney size in children: a pilot study of renal length as a surrogate of organ growth" 대한소아과학회 55 (55): 54-57, 2012

16 Moghazi S, "Correlation of renal histopathology with sonographic findings" 67 : 1515-1520, 2005