Fabrication of Perfluoropolyether Microfluidic Devices Using Laser Engraving for Uniform Droplet Production

다국어 초록 (Multilingual Abstract)

In this study, we fabricated a perfluoropolyether (PFPE)-based microfluidic device equipped with cross-junction microchannels for the purpose of generating uniform droplets. The microchannels were engraved using CO2 laser. PFPE was selected as the main material due to its superior solvent resistance, polyethylene glycol diacrylate (PEGDA) was blended with PFPE to make a hydrophilic surface of the microchannels. The microchannels of the polydimethylsiloxane microfluidic device exhibited a blackened and rough surface after laser engraving. On the other hand, PFPE-PEGDA microfluidic device had a smooth internal surface. In particular, microchannels with smaller dimensions of less than 30 µm in depth were developed by laser engraving of lower power and higher speed. Both PFPE and PFPE- PEGDA microfluidic devices demonstrated efficacy in producing uniform water and oil droplets, respectively. This PFPE-based microfluidic device equipped with CO2 laser-engraved microchannels show promise for diverse applications including biological and chemical analysis, extraction, and synthesis processes.

목차 (Table of Contents)

• Contents i
• List of figures·ⅲ
• Abstract 1
• Introduction 2
• Materials and Methods 7
• Results and Discussion 11
• Conclusion 18
• References20