관상동맥 조영술시 심전도에 미치는 조영제 (Hexabrix와 Urografin 76)의 영향에 관한 비교 연구 = Comparison of the Effect of Hexabrix and Urografin 76 on Q-T Interval and ST-T wave of ECG during Coronary Angiography

다국어 초록 (Multilingual Abstract)

Background: Complications such as braycardia, changes of T wave, R-R interval, QRS comples and S-T segment, premature atrial contracture, premature vetricular contracture ventricular tachycardia on ECG during coronary angiography may happen. They are somewhat caused by osmolarity, inoic concetration of Na^(+) and H^(+), molecular weight of contrast dye and the change of coronary artery pressure during coronary angiography. Methods: We compared the changes of Q-Tc interval, S-T segment and T wave during coronary angiography between high somolar(Urografin 76) and low osmolar contrast dye(Hexabrix). The 32 patients with chest pain were studied and ECG was checked before and 1, 2, 5 minute after and right coronary angiography. Results: 1) There was no significant difference in change of S-T wave between the two groups during left coronary angiography. And there was also no significant difference in change of S-T wave during right coronary angigraphy. 2) The maximal prolongation of Q-Tc interval during left coronary angiography was 6.8 seconds in high osmolar group and 6.0 seconds in low osmolar group. The maximal prolongation of Q-Tc interval during right coronary angiogrphy was 7.7 seconds in high osmolar group and 6.3 seconds in low osmolar group. 3) There was significant prolongation of Q-Tc interval in high osmolar group(0.078±0.042 seconds) than that of low osmolar group(0.053±0.028 seconds) during left coronary angiography(p<0.01). But the change of Q-Tc interval during right coronary angiography was not significantly different. Conclusions: The prolongation of Q-Tc interval was more increased in high osmolar contrast media group than in low osmolar. So the low osmolar contrast media was safer than high osmolar contrast media and it need close observation espeically 6-8 seconds after injection of contrast media to prevent arrthythmia and other complications.