Quantitative estimation of UV light dose concomitant to irradiation with ionizing radiation

다국어 초록 (Multilingual Abstract)

A simple mathematical model for biological estimation of UV light dose concomitant to ionizing radiation was suggested. This approach was applied to determine the dependency of equivalent UV light dose accompanied by 100Gy of ionizing radiation on energy of sparsely ionizing radiation and on volume of the exposed cell suspension. It was revealed that the relative excitation contribution to the total lethal effect and the value of UV dose was greatly increased with an increase in energy of ionizing radiation and volume of irradiated suspensions. It is concluded that these observations are in agreement with the supposition that Cerenkov emission is responsible for the production of UV light damage and the phenomenon of photoreactivation observed after ionizing exposure of bacterial and yeast cells hypersensitive to UV light. A possible synergistic interaction of the damages produced by ionizations and excitations as well as a probable participation of UV component of ionizing radiation in the mechanism of hormesis and adaptive response observed after ionizing radiation exposure is discussed.