판누스 형성이 인공심장밸브와 대동맥 혈류에 미치는 혈류역학적 영향: 전산 유체 역학 해석

다국어 초록 (Multilingual Abstract)

Although hemodynamic effects of generation of sub-prosthetic tissue called pannus formation can affect the function of prosthetic heart valves, little has been reported about their relationship. In this study, we aimed to demonstrate the effects of the pannus formation in prosthetic heart valves by using computational fluid dynamics (CFD) using Flow Vision. The results show that the pannus formation in the prosthetic heart valve influenced the transvalvular peak velocity, transvalvular pressure gradient (TPG) and opening angle through the prosthetic heart valves. The width of the pannus about 25% of the vessel diameter reduced the opening angle of the prosthetic valve from 85° to 69°, increased the transvalvular peak velocity up to 4.3 m/s, and increased pressure loss through the valve up to 108.1 mmHg. Pressure gradient estimation based on the Bernoulli equation (P-TPG) and the CFD computed pressure (P-CFD) showed minor discrepancy but linearly agreed in general.

목차 (Table of Contents)

• Abstract
• 1. 서론
• 2. 실험 방법
• 3. 결과
• 4. 결론
• 참고문헌