Peritomeal clearances of urea(Curea) and creatinine(Ccr), glucose absorption, dialysate glucose concentration, and peritoneal ultrafiltration volume(UF) were measured in 21 CAPD patients who had been on dialysis for 7 days to 41 months (mean 19.7 mo.)...
Peritomeal clearances of urea(Curea) and creatinine(Ccr), glucose absorption, dialysate glucose concentration, and peritoneal ultrafiltration volume(UF) were measured in 21 CAPD patients who had been on dialysis for 7 days to 41 months (mean 19.7 mo.) to investigate the effect of time on CAPD on the peritoneal solute clearance and ultrafiltration. Curea, Ccr. And UF all correlated inversely with on CAPD. Number of peritonitis increased with time but did not correlate with Curea, Ccr of UF. Peritoneal glucose absorption did not correlate with time on CAPD although a positive correlation betwecn dialysate glucose concentration and time on CAPD suggests that glucose absorption may decrease with time.
The results of tbis cross sectional study suggest that peritoneal solute transport, as assessed by urea and creatininc clearances, and peritoneal ultrafiltration may decrease with time in longterm CAPD patients. Simultaneous decreases in solute transport and ultrafiltration suggest decrease in membrane area and permeability.