Microbacterium 에 의한 중심정맥관 연관 균혈증 1예: 16S rRNA 유전자 염기서열분석을 이용한 균 동정 = Central Venous Catheter-Related Microbacterium Bacteremia Identified by 16S ribosomal RNA Gene Sequencing

다국어 초록 (Multilingual Abstract)

We describe here a case of central venous catheter
(CVC)-related bacteremia caused by Microbacterium
species in a 14-year-old patient, who had received
chemotherapy for acute lymphoblastic leukemia. All nine
blood cultures obtained from admission day 2 to day 62
yielded the same yellow-pigmented coryneform rod.
Both Vitek 2 (bioMerieux, USA) and MicroScan (Dade
Behring, USA) identified the isolate as Micrococcus
species, and the API Coryne (bioMerieux, France)
identified the isolate as Rhodococcus or Brevibacterium
species. However, the 16S rRNA gene sequence
showed a 99% identity with Microbacterium
species. The bacteremia was recurrent or persistent
over 60 days despite alternate systemic antibiotic
therapy, but blood culture became negative after an
addition of teicoplanin lock therapy for eradicating
CVC-related bacteremia. This represents the first report
of CVC-related Microbacterium bacteremia cured
by antibiotic lock therapy in Korea.

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