Propofol-Fentanyl 정맥마취의 임상적 유용성 = Clinical Usefulness of Propofol-Fentanyl Intravenous Anesthesia

다국어 초록 (Multilingual Abstract)

Background： Propofol is being increasingly used a公 a intravenous anesthetic, but has no remarkable analgesic effect.




Previous reports demonstrated that using of propofol with opioids had synergic effects, and decreased requiring dose of propofol. The purpose of this study was Co examine the clinical usefulness of propofo卜fentanyl intravenous anesthesia. Methods: Sixty patients of ASA status I or II undergoing breast mass excision were studied. Intravenous anesthesia was induced with fentanyl (2 ug/kg) and bolus dose of propofol (2 mg/kg) and maintained with continuous infusion of propofol (6-10 mg/kg八irk We measured loading, maintenance and total doses of propofol，changes of blood pressure, anesthesia time，and also observed the incidences of side effects of propofol anesthesia. Results: The bolus dose of propofol was administered within average injection time of 61.2 seconds. The systolic and diastolic pressure were significantly decreased after bolus injection of propofol (p<0.05). The administered total dose of propofol was 292.4 ±77.9 mg during average anesthesia time of 27,3 minutes. The incidences of injection pain, apnea and dizziness were 46,7%，38.3% and 25% respectively. Conclusion: We concluded that the propofol-fentanyl intravenous anesthesia using infusion pump was clinically useful and safe method for short time operation.