Subcutaneous panniculitis-like T-cell lymphoma (SPTL) is an infrequent cytotoxic T-cell lymphoma of the skin with a unique immunophenotypic profile. Here we describe this lymphoma in a 7-year-old boy. He presented with erythematous swelling like a cel...
Subcutaneous panniculitis-like T-cell lymphoma (SPTL) is an infrequent cytotoxic T-cell lymphoma of the skin with a unique immunophenotypic profile. Here we describe this lymphoma in a 7-year-old boy. He presented with erythematous swelling like a cellulitis, clinically, on his both cheek. Histopathological findings revealed lobular infiltration of atypical lymphoid cells in subcutaneous tissue, especially around individual fat cells. Immunohistochemical evaluation of the atypical lymphocytes showed CD3 and CD8 immunoreactivity and CD4 and CD56 negativity. By genetic analysis, He showed βF-1/T-cell receptor gene clonal rearrangement. He was diagnosed as SPTL based on clinical, histopathological and immunohistochemical findings. This report suggests that SPTL should be added to the differential diagnosis of patients with refractory and recurrent facial swelling.