한국산 족부 백선균의 항진균제 감수성에 관한 연구 = Study on Antifungal Susceptibility of Tinea Pedis Isolated from Korea

다국어 초록 (Multilingual Abstract)

Minimum inhibitory concentration(MIC) of griseofulvin, imidazole derivatives such as ketoconazole, econazole, miconazole and itraconazole on 52 strains of Trichophyton ruhrum, 22 strains of T. mentagraphytes, 10 strains of Microsporum spp. and 1 strain of Epidermophyton floccosum were determined after one week of incubation at 25C on Sabouraud dextrose broth. The results were summarized as followes :
1. The MICs of griseofulvin against 4 different tinea pedis fungi were ranged from 10-100mcg/ml. This values indicated that effectiveness of antifungal activity were relatively lower than those of three other imidazole derivatives such as ketoconazole, econazole, miconazole and one itraconazole.
2. Out of three imidazole derivatives, econazole had relatively higher inhibitory
concentrations with 0.1-10mcg/ml against all tinea pedis isolated.
3. Out of 5 antifungal agents, itraconazole which is trizole derivatives showed the highest inhibitory activity with 0.1-10mcg/ml against all tinea pedis tested.
4. These results indicated that inhibitory activity of griseofulvin against tinea pedis were lower than those of four other antifungal agents tested. But these four antifungal agents such as ketoconazole, econazole, miconazole and. itraconazole were effective against tinea pedis tested.

목차 (Table of Contents)

• ABSTRACT = 13
• Ⅰ. 서론 = 14
• Ⅱ. 재료 및 방법 = 14
• 1. 재료 = 14
• 2. 방법 = 14
• Ⅲ. 결과 = 15
• Ⅳ. 고찰 = 17
• Ⅴ. 결론 = 18
• 참고문헌 = 19